Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19762488 | 0.83 | — | — | |
| SCHEMBL9849583 | 0.80 | NOTUM (0.42) | PPARACHRNB2CHRNA4NOTUM | |
| SCHEMBL18256145 | 0.80 | PPARA (0.43) | PPARACHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL9548364 | 0.78 | NOTUM (0.41) | PPARACHRNB2CHRNA4NOTUM | |
| SCHEMBL8605589 | 0.76 | PPARA (0.57) | PPARA | |
| SCHEMBL11454209 | 0.75 | — | — | |
| SCHEMBL19762489 | 0.75 | — | — | |
| SCHEMBL19598757 | 0.74 | PPARA (0.49) | PPARA | |
| SCHEMBL7502255 | 0.74 | PPARA (0.60) | PPARA | |
| SCHEMBL18256179 | 0.72 | PPARA (0.43) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200375950-A1 | 1H-PYRAZOLO[4,3-B]PYRIDINES AS PDE1 INHIBITORS | H. LUNDBECK A/S (DK) | 2020-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200375950-A1 | 1H-PYRAZOLO[4,3-B]PYRIDINES AS PDE1 INHIBITORS | PDE12, PDE3A, PDE5A | PPARA 2070/4885CHRNB2 109/4885CHRNA4 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.