Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1370906 | 0.75 | KDM4E (0.45) | NUDT1 | |
| SCHEMBL29485626 | 0.75 | KDM4E (0.45) | NUDT1 | |
| SCHEMBL28182837 | 0.74 | KDM4E (0.44) | NUDT1 | |
| SCHEMBL22717083 | 0.71 | ADORA2A (0.42) | NUDT1 | |
| SCHEMBL17732805 | 0.67 | IKBKB (0.41) | — | |
| SCHEMBL5798064 | 0.66 | — | — | |
| SCHEMBL11922160 | 0.64 | TNKS (0.40) | — | |
| SCHEMBL24659084 | 0.63 | NUDT1 (0.35) | NUDT1 | |
| SCHEMBL15644331 | 0.63 | NUDT1 (0.35) | NUDT1 | |
| SCHEMBL2010215 | 0.62 | NUDT1 (0.34) | NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976038-A1 | HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS | Angex Pharmaceutical, Inc. (US) | 2022-04-06 | — | — | EP | disclosed |
| WO-2020243178-A1 | HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS | ANGEX PHARMACEUTICAL, INC. (US) | 2020-12-03 | — | — | WO | disclosed |