Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | AKR1C3 | P42330 | 13/20 | 0.61 |
| ▸ | AKR1C2 | P52895 | 13/20 | 0.61 |
| ▸ | DHODH | Q02127 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | FABP3 | P05413 | 1/20 | 0.57 |
| ▸ | FABP4 | P15090 | 1/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22720113 | 0.92 | MEN1 (0.72) | MEN1LMNAKMT2AMAPTPOLB | |
| SCHEMBL9593591 | 0.88 | AKR1C3 (0.79) | MEN1LMNAKMT2AMAPTPOLB | |
| SCHEMBL9595705 | 0.88 | AKR1C3 (0.71) | MEN1LMNAKMT2AMAPTPOLB | |
| SCHEMBL9594435 | 0.87 | AKR1C3 (0.73) | MEN1LMNAKMT2AMAPTPOLB | |
| SCHEMBL11108122 | 0.86 | AKR1C3 (0.72) | MEN1LMNAKMT2AMAPTPOLB | |
| SCHEMBL9594507 | 0.85 | AKR1C3 (0.82) | MEN1LMNAKMT2AMAPTPOLB | |
| SCHEMBL22720189 | 0.84 | AKR1C3 (0.71) | MEN1LMNAKMT2AMAPTPOLB | |
| SCHEMBL7851947 | 0.83 | MEN1 (0.59) | MEN1LMNAKMT2AMAPTPOLB | |
| SCHEMBL22720157 | 0.83 | AKR1C3 (0.62) | MEN1LMNAKMT2AMAPTPOLB | |
| SCHEMBL6141457 | 0.83 | AKR1C3 (0.70) | MEN1LMNAKMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110229114-B | Remove C2-toSymmetric diphenylamine type chiral bisoxazoline ligand and synthetic method and application thereof | 浙江工业大学 | 2021-07-27 | — | — | CN | disclosed |
| WO-2020238559-A1 | DE-C2-SYMMETRIC DIPHENYLAMINE-TYPE CHIRAL BISOXAZOLINE LIGAND, SYNTHESIS METHOD THEREFOR AND USE THEREOF | 浙江工业大学 | 2020-12-03 | — | — | WO | disclosed |