Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 5/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20337418 | 0.86 | USP2 (0.43) | USP2SMN1; SMN2GPR119HPGDEPHX2 | |
| SCHEMBL31184198 | 0.86 | USP2 (0.43) | USP2SMN1; SMN2GPR119HPGDEPHX2 | |
| SCHEMBL8217780 | 0.79 | USP2 (0.50) | USP2SMN1; SMN2GPR119HPGDEPHX2 | |
| SCHEMBL16984146 | 0.79 | USP2 (0.50) | USP2SMN1; SMN2GPR119HPGDEPHX2 | |
| SCHEMBL30577865 | 0.76 | GPR119 (0.38) | USP2SMN1; SMN2GPR119HPGDEPHX2 | |
| SCHEMBL24170473 | 0.76 | HPGD (0.48) | USP2SMN1; SMN2GPR119HPGDEPHX2 | |
| SCHEMBL30842433 | 0.75 | USP2 (0.50) | USP2SMN1; SMN2GPR119HPGDEPHX2 | |
| SCHEMBL1344048 | 0.75 | USP2 (0.50) | USP2SMN1; SMN2GPR119HPGDEPHX2 | |
| SCHEMBL22799171 | 0.75 | HPGD (0.47) | USP2SMN1; SMN2GPR119HPGDEPHX2 | |
| SCHEMBL21807018 | 0.74 | USP2 (0.49) | USP2SMN1; SMN2GPR119HPGDEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3753941-A1 | PYRIMIDINE-FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Blueray Biopharma Co., Ltd. (CN) | 2020-12-23 | — | — | EP | disclosed |
| WO-2020239123-A1 | AROMATIC HETEROCYCLIC DERIVATIVE MODULATOR AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-03 | — | — | WO | disclosed |