Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.45 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22720339 | 1.00 | ABCB1 (0.45) | ABCB1SMARCA2SMARCA4PBRM1GPR119 | |
| SCHEMBL30957841 | 0.90 | ABCB1 (0.44) | ABCB1SMARCA2SMARCA4PBRM1GPR119 | |
| SCHEMBL22724584 | 0.90 | ABCB1 (0.44) | ABCB1SMARCA2SMARCA4PBRM1GPR119 | |
| SCHEMBL24851280 | 0.85 | SMARCA2 (0.45) | ABCB1SMARCA2SMARCA4PBRM1GPR119 | |
| SCHEMBL24091357 | 0.83 | GPR119 (0.50) | ABCB1SMARCA2SMARCA4PBRM1GPR119 | |
| SCHEMBL12486516 | 0.82 | SMARCA2 (0.45) | ABCB1SMARCA2SMARCA4PBRM1GPR119 | |
| SCHEMBL12486518 | 0.82 | SMARCA2 (0.45) | ABCB1SMARCA2SMARCA4PBRM1GPR119 | |
| SCHEMBL3804885 | 0.82 | CKS1B (0.50) | GPR119MAPTLMNAPOLBCKS1B | |
| SCHEMBL908219 | 0.81 | ABCB1 (0.48) | ABCB1SMARCA2SMARCA4PBRM1GPR119 | |
| SCHEMBL908218 | 0.81 | ABCB1 (0.48) | ABCB1SMARCA2SMARCA4PBRM1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113396147-B | Aromatic heterocyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-113396147-A | Aromatic heterocyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-09-14 | — | — | CN | disclosed |
| WO-2020239123-A1 | AROMATIC HETEROCYCLIC DERIVATIVE MODULATOR AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-03 | — | — | WO | disclosed |