SCHEMBL2272090

SCHEMBL2272090

OB(O)CCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7647616 0.78 THRB (0.39)
SCHEMBL6883366 0.67
Boric Acid SCHEMBL10950163 0.63
SCHEMBL7649020 0.59
SCHEMBL4066708 0.59
SCHEMBL3212417 0.59
SCHEMBL17946280 0.56
SCHEMBL11766376 0.54
SCHEMBL6324774 0.54
SCHEMBL537874 0.54

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250236632-A1 BETA-LACTAMASE INHIBITORS VENATORX PHARMACEUTICALS INC (US) 2025-07-24 US disclosed
EP-3922635-A1 BETA-LACTAMASE INHIBITORS Venatorx Pharmaceuticals, Inc. (US) 2021-12-15 EP disclosed
EP-2928898-B1 BETA-LACTAMASE INHIBITORS VENATORX PHARMACEUTICALS INC (US) 2021-04-14 EP disclosed
US-10669290-B2 Beta-lactamase inhibitors VenatoRx Pharmaceuticals, Inc. (US) 2020-06-02 US disclosed
CN-111117555-A Environment-friendly aqueous adhesive and preparation method thereof 庄明磊 2020-05-08 CN disclosed
US-20190225628-A1 BETA-LACTAMASE INHIBITORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2019-07-25 US disclosed
US-10335425-B2 Compositions and methods of treating of bacterial infections with β-lactamase inhibitors CASE WESTERN RESERVE UNIVERSITY (US) 2019-07-02 US disclosed
US-20180256614-A1 COMPOSITIONS AND METHODS OF TREATING OF BACTERIAL INFECTIONS WITH BETA-LACTAMASE INHIBITORS CASE WESTERN UNIVERSITY 2018-09-13 US disclosed
US-20180194783-A1 BETA-LACTAMASE INHIBITORS VenatoRx Pharmaceuticals, Inc. 2018-07-12 US disclosed
US-9949995-B2 Compositions and methods of treating of bacterial infections with β-lactamase inhibitors CASE WESTERN RESERVE UNIVERSITY (US) 2018-04-24 US disclosed
US-8557980-B2 Methods for forming protected organoboronic acids THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2013-10-15 US disclosed
WO-2011103435-A2 METHODS FOR FORMING PROTECTED ORGANOBORONIC ACIDS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2011-08-25 WO disclosed
US-20110201806-A1 Methods for Forming Protected Organoboronic Acids NATIONAL SCIENCE FOUNDATION 2011-08-18 US disclosed
US-7122627-B2 Lactam inhibitors of Hepatitis C virus NS3 protease BRISTOL-MYERS SQUIBB COMPANY (US) 2006-10-17 US disclosed
US-20040171556-A1 Methods for inhibiting proteasome BRISTOL-MYERS SQUIBB COMPANY 2004-09-02 US disclosed
US-20030008828-A1 Diagnostic kits; for therapy of viral infection; as assat standard or reagent BRISTOL-MYERS SQUIBB COMPANY 2003-01-09 US disclosed
EP-1206449-A1 LACTAM INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE BRISTOL-MYERS SQUIBB COMPANY (US) 2002-05-22 EP disclosed
EP-1196436-A2 PEPTIDE BORONIC ACID INHIBITORS OF HEPATITIS C VIRUS PROTEASE Bristol-Myers Squibb Pharma Company (US) 2002-04-17 EP disclosed
WO-2001007407-A1 LACTAM INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2001-02-01 WO disclosed
WO-2001002424-A2 PEPTIDE BORONIC ACID INHIBITORS OF HEPATITIS C VIRUS PROTEASE DU PONT PHARMACEUTICALS COMPANY (US) 2001-01-11 WO disclosed