Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29539556 | 1.00 | NPSR1 (0.51) | NPSR1KDM4EALDH1A1LMNAALOX5 | |
| SCHEMBL29539552 | 1.00 | NPSR1 (0.51) | NPSR1KDM4EALDH1A1LMNAALOX5 | |
| SCHEMBL22721877 | 0.95 | NPSR1 (0.48) | NPSR1KDM4EALDH1A1LMNAALOX5 | |
| SCHEMBL29539559 | 0.95 | NPSR1 (0.48) | NPSR1KDM4EALDH1A1LMNAALOX5 | |
| SCHEMBL29539637 | 0.92 | ALOX5 (0.58) | NPSR1KDM4EALDH1A1LMNAALOX5 | |
| SCHEMBL22721778 | 0.92 | ALOX5 (0.58) | NPSR1KDM4EALDH1A1LMNAALOX5 | |
| SCHEMBL22721783 | 0.90 | NPSR1 (0.53) | NPSR1KDM4EALDH1A1LMNAALOX5 | |
| SCHEMBL29539482 | 0.90 | NPSR1 (0.53) | NPSR1KDM4EALDH1A1LMNAALOX5 | |
| SCHEMBL22721536 | 0.89 | NPSR1 (0.59) | NPSR1KDM4EALDH1A1LMNAALOX5 | |
| SCHEMBL29539598 | 0.89 | NPSR1 (0.59) | NPSR1KDM4EALDH1A1LMNAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113840820-B | Phthalazinone compounds and uses thereof | ST制药株式会社 | 2024-05-03 | — | — | CN | claimed |
| CN-113840820-A | Phthalazinone compounds and uses thereof | ST制药株式会社 | 2021-12-24 | — | — | CN | claimed |
| WO-2020242245-A1 | PHTHALAZINONE COMPOUNDS AND USE THEREOF | 에스티팜 주식회사 | 2020-12-03 | — | — | WO | claimed |
| CN-113840820-B | Phthalazinone compounds and uses thereof | ST制药株式会社 | 2024-05-03 | — | — | CN | disclosed |
| EP-3978480-A1 | PHTHALAZINONE COMPOUNDS AND USE THEREOF | ST Pharm Co., Ltd. (KR) | 2022-04-06 | — | — | EP | disclosed |
| CN-113840820-A | Phthalazinone compounds and uses thereof | ST制药株式会社 | 2021-12-24 | — | — | CN | disclosed |
| WO-2020242245-A1 | PHTHALAZINONE COMPOUNDS AND USE THEREOF | 에스티팜 주식회사 | 2020-12-03 | — | — | WO | disclosed |