SCHEMBL2272191

SCHEMBL2272191

CNC(CC[SiH3])(c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.46
CYP2D6 P10635 2/20 0.36
LMNA P02545 1/20 0.36
TSHR P16473 1/20 0.36
TAAR1 Q96RJ0 1/20 0.34
KIF11 P52732 3/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MAPK1 P28482 1/20 0.32
CYP2C19 P33261 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2C9 P11712 1/20 0.32
KCNH2 Q12809 1/20 0.32
HIF1A Q16665 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28113805 0.81 KCNN4 (0.48) KCNN4CYP2D6LMNATSHRTAAR1
SCHEMBL2272802 0.80 KCNN4 (0.53) KCNN4LMNATAAR1KIF11SMN1; SMN2
SCHEMBL2101646 0.79 KCNN4 (0.46) KCNN4CYP2D6LMNATSHRTAAR1
SCHEMBL14533616 0.74 KCNN4 (0.50) KCNN4CYP2D6LMNATAAR1MAPK1
Hydrochloric Acid SCHEMBL27715222 0.72 TAAR1 (0.50) KCNN4CYP2D6LMNATAAR1KIF11
SCHEMBL27941327 0.71 KCNN4 (0.38) KCNN4CYP2D6TAAR1KIF11CYP2C19
Hydrochloric Acid SCHEMBL6986086 0.69 GBA1 (0.45) CYP2D6LMNA
SCHEMBL2102354 0.69 TSHR (0.48) KCNN4TSHRTAAR1KIF11SMN1; SMN2
SCHEMBL2102971 0.68 KCNN4 (0.53) KCNN4LMNATAAR1KIF11SMN1; SMN2
SCHEMBL2276136 0.67 TSHR (0.46) KCNN4CYP2D6TSHRTAAR1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed