Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SELL | P14151 | 1/20 | 0.39 |
| ▸ | SELP | P16109 | 1/20 | 0.39 |
| ▸ | SELE | P16581 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12436723 | 1.00 | MTNR1A (0.44) | MTNR1AMTNR1BFASNSMN1; SMN2KMT2A | |
| SCHEMBL256673 | 0.89 | — | — | |
| SCHEMBL11682924 | 0.89 | MTNR1A (0.50) | MTNR1AMTNR1BFASNSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL28162204 | 0.87 | — | — | |
| SCHEMBL12436696 | 0.86 | KMT2A (0.40) | SMN1; SMN2KMT2ANPSR1EPHX2HPGD | |
| SCHEMBL12513739 | 0.86 | KMT2A (0.40) | SMN1; SMN2KMT2ANPSR1EPHX2HPGD | |
| SCHEMBL16383659 | 0.85 | MTNR1A (0.45) | MTNR1AMTNR1BFASNSMN1; SMN2KMT2A | |
| SCHEMBL16892296 | 0.83 | SELL (0.54) | MTNR1AMTNR1BFASNSMN1; SMN2KMT2A | |
| SCHEMBL31640052 | 0.83 | FASN (0.44) | MTNR1AMTNR1BFASNSMN1; SMN2KMT2A | |
| SCHEMBL18214990 | 0.83 | SELL (0.54) | MTNR1AMTNR1BFASNSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49686-E1 | Nitrogen-containing heterocyclic compound and use of same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-10 | — | — | US | disclosed |
| WO-2022115719-A1 | PD-L1 BINDING PEPTIDES AND PEPTIDE COMPLEXES AND METHODS OF USE THEREOF | FRED HUTCHINSON CANCER RESEARCH CENTER (US) | 2022-06-02 | — | — | WO | disclosed |
| US-RE48334-E1 | Nitrogen-containing heterocyclic compound and use of same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-12-01 | — | — | US | disclosed |