Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 11/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12436784 | 1.00 | EPHX2 (0.56) | EPHX2EPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12513746 | 0.89 | EPHX2 (0.46) | EPHX2EPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14528029 | 0.89 | EPHX2 (0.46) | EPHX2EPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12436833 | 0.86 | ATM (0.47) | EPHX2EPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22722029 | 0.86 | ATM (0.47) | EPHX2EPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12436014 | 0.86 | ATM (0.47) | EPHX2EPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22722007 | 0.84 | EPHX1 (0.47) | EPHX2EPHX1KDM4EALDH1A1KMT2A | |
| SCHEMBL12436769 | 0.84 | EPHX1 (0.47) | EPHX2EPHX1KDM4EALDH1A1KMT2A | |
| SCHEMBL22722039 | 0.84 | POLB (0.57) | EPHX2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL572180 | 0.84 | POLB (0.43) | EPHX2EPHX1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49686-E1 | Nitrogen-containing heterocyclic compound and use of same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-10 | — | — | US | disclosed |
| US-RE48334-E1 | Nitrogen-containing heterocyclic compound and use of same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-12-01 | — | — | US | disclosed |