Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.35 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22716997 | 0.91 | PDE3B (0.39) | DHODHNR4A2PDE3BPDE3APTGDR2 | |
| SCHEMBL29454537 | 0.91 | PDE3B (0.39) | DHODHNR4A2PDE3BPDE3APTGDR2 | |
| SCHEMBL22717230 | 0.85 | PDE3B (0.38) | DHODHNR4A2PDE3BPDE3APTGDR2 | |
| SCHEMBL22716998 | 0.82 | PTGDR2 (0.38) | DHODHNR4A2PTGDR2SLC13A5SORT1 | |
| SCHEMBL29454553 | 0.82 | PTGDR2 (0.38) | DHODHNR4A2PTGDR2SLC13A5SORT1 | |
| SCHEMBL29454662 | 0.77 | FFAR1 (0.47) | — | |
| SCHEMBL22717217 | 0.77 | FFAR1 (0.47) | — | |
| SCHEMBL22717219 | 0.77 | FFAR1 (0.47) | — | |
| SCHEMBL22717172 | 0.76 | NR4A2 (0.40) | DHODHNR4A2PDE3BPDE3APTGDR2 | |
| SCHEMBL22717049 | 0.75 | NNMT (0.41) | DHODHAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020242943-A1 | GPR40 AGONISTS | KALLYOPE, INC. (US) | 2020-12-03 | — | — | WO | disclosed |