SCHEMBL2272677

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2221970	0.93	CXCR3 (0.67)	CXCR3EPHX2NPC1RAB9AUSP30
	SCHEMBL2221638	0.92	CXCR3 (0.78)	CXCR3EPHX2USP30MEN1KMT2A
	SCHEMBL2223502	0.90	CXCR3 (0.56)	CXCR3EPHX2SLC2A1NPC1RAB9A
	SCHEMBL2223650	0.87	CXCR3 (0.85)	CXCR3SLC2A1NPC1RAB9AF10
	SCHEMBL12516581	0.86	CXCR3 (0.67)	CXCR3NPC1RAB9AMEN1KMT2A
	SCHEMBL2271834	0.86	CXCR3 (0.60)	CXCR3EPHX2NPC1RAB9AMEN1
	SCHEMBL2266970	0.85	CXCR3 (0.64)	CXCR3MEN1KMT2AKCNQ3KCNQ2
	SCHEMBL2267018	0.84	CXCR3 (0.68)	CXCR3NPC1RAB9AMEN1KMT2A
	SCHEMBL12515722	0.83	CXCR3 (0.72)	CXCR3NPC1RAB9AMEN1KMT2A
	SCHEMBL2267498	0.83	CXCR3 (0.72)	CXCR3SLC2A1NPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.