Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.55 |
| ▸ | CSNK1A1 | P48729 | 5/20 | 0.55 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.49 |
| ▸ | IKZF2 | Q9UKS7 | 10/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22713350 | 0.94 | CRBN (0.57) | CRBNCSNK1A1GSPT1CYP2C19KCNH2 | |
| SCHEMBL22713354 | 0.94 | CRBN (0.57) | CRBNCSNK1A1GSPT1CYP2C19KCNH2 | |
| SCHEMBL22713502 | 0.91 | CRBN (0.55) | CRBNCSNK1A1GSPT1CYP2C19KCNH2 | |
| SCHEMBL22713500 | 0.91 | CRBN (0.55) | CRBNCSNK1A1GSPT1CYP2C19KCNH2 | |
| SCHEMBL22713249 | 0.90 | CRBN (0.53) | CRBNCSNK1A1GSPT1CYP2C19KCNH2 | |
| SCHEMBL22713258 | 0.90 | CRBN (0.53) | CRBNCSNK1A1GSPT1CYP2C19KCNH2 | |
| SCHEMBL22713343 | 0.89 | CRBN (0.53) | CRBNCSNK1A1GSPT1CYP2C19KCNH2 | |
| SCHEMBL22713337 | 0.89 | CRBN (0.53) | CRBNCSNK1A1GSPT1CYP2C19KCNH2 | |
| SCHEMBL29486617 | 0.89 | CRBN (0.53) | CRBNCSNK1A1GSPT1CYP2C19KCNH2 | |
| SCHEMBL22713534 | 0.87 | CRBN (0.57) | CRBNCSNK1A1GSPT1CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243379-A1 | SUBSTITUTED 1-OXO-ISOINDOLINE-5-CARBOXAMIDE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | CELGENE CORPORATION (US) | 2020-12-03 | — | — | WO | disclosed |