SCHEMBL2272827

SCHEMBL2272827

CCCC[SiH](CCC)CCN(C)C

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 5/20 0.44
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10415307 0.82 TSHR (0.40) ALDH1A1TSHR
SCHEMBL20576383 0.82 TSHR (0.40) ALDH1A1TSHR
SCHEMBL15533414 0.82 TSHR (0.40) ALDH1A1TSHR
SCHEMBL2270116 0.79 PLA2G1B (0.32)
SCHEMBL153638 0.76 TSHR (0.46) DNM1ALDH1A1TSHR
SCHEMBL27801423 0.73 TSHR (0.44) DNM1ALDH1A1TSHR
SCHEMBL708607 0.73 TSHR (0.33) ALDH1A1TSHR
SCHEMBL706848 0.73 TSHR (0.43) DNM1ALDH1A1TSHR
SCHEMBL702940 0.73 TSHR (0.43) DNM1ALDH1A1TSHR
SCHEMBL10423271 0.73 TSHR (0.43) DNM1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed