SCHEMBL2272875

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Trifluoroacetic Acid SCHEMBL3634018	0.90	NPC1 (0.52)	NPC1RAB9AALDH1A1HPGDKDM4E
	SCHEMBL1957530	0.84	MAPK1 (0.61)	RAB9AALDH1A1HPGDKDM4ESMN1; SMN2
	SCHEMBL1422546	0.82	NPC1 (0.73)	NPC1RAB9AALDH1A1HPGDKDM4E
	SCHEMBL1422965	0.82	NPC1 (0.71)	NPC1RAB9AALDH1A1HPGDKDM4E
	SCHEMBL13197417	0.81	NPC1 (0.74)	NPC1RAB9AALDH1A1HPGDKDM4E
	SCHEMBL1422694	0.80	NPC1 (0.72)	NPC1RAB9AALDH1A1HPGDKDM4E
	SCHEMBL1422514	0.80	NPC1 (0.72)	NPC1RAB9AALDH1A1HPGDKDM4E
	SCHEMBL29032391	0.78	KDM4E (0.64)	NPC1RAB9AALDH1A1HPGDKDM4E
	SCHEMBL1423243	0.77	NPC1 (1.00)	NPC1RAB9AALDH1A1HPGDKDM4E
	SCHEMBL12171570	0.77	NR4A2 (0.70)	NPC1RAB9AALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.