Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448243 | 0.83 | — | — | |
| SCHEMBL25134507 | 0.83 | — | — | |
| SCHEMBL21426014 | 0.79 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL22213505 | 0.77 | CYP19A1 (0.38) | CYP19A1TSHRNPSR1HSD17B10KDM4E | |
| SCHEMBL17980313 | 0.77 | — | — | |
| SCHEMBL6124723 | 0.77 | — | — | |
| SCHEMBL19534246 | 0.77 | CYP19A1 (0.40) | CYP19A1HSD11B1 | |
| Hydrochloric Acid SCHEMBL26618937 | 0.75 | CYP19A1 (0.33) | CYP19A1TSHRNPSR1 | |
| SCHEMBL28056833 | 0.73 | TSHR (0.31) | TSHRNPSR1 | |
| SCHEMBL23059249 | 0.73 | TSHR (0.31) | TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3744718-A1 | HIGHLY ACTIVE CSF1R INHIBITOR COMPOUND | Adlai Nortye Biopharma Co., Ltd. (CN) | 2020-12-02 | — | — | EP | disclosed |