SCHEMBL28056833

SCHEMBL28056833

CC1(C[SH](=O)=O)CCNC1=O

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25134507 0.77
SCHEMBL7448243 0.77
SCHEMBL17980313 0.75
SCHEMBL6124723 0.75
Hydrochloric Acid SCHEMBL26618937 0.73 CYP19A1 (0.33) TSHRNPSR1
SCHEMBL22728952 0.73 CYP19A1 (0.39) TSHRNPSR1
SCHEMBL23059249 0.72 TSHR (0.31) TSHRNPSR1
SCHEMBL14378068 0.71 TSHR (0.34) TSHRNPSR1
SCHEMBL21426014 0.69 CYP19A1 (0.31)
SCHEMBL28187999 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110016020-A Compound or pharmaceutically acceptable salt thereof, application and pharmaceutical composition thereof 铁木医药有限公司 2019-07-16 CN disclosed
CN-109384778-A Use of a compound or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for the treatment of a disease, health condition or disorder 铁木医药有限公司 2019-02-26 CN disclosed
CN-109369635-A Compound or pharmaceutically acceptable salt thereof, application and pharmaceutical composition thereof 铁木医药有限公司 2019-02-22 CN disclosed
CN-108912111-A compounds and pharmaceutical compositions 铁木医药有限公司 2018-11-30 CN disclosed
CN-105408328-B sGC stimulators 铁木医药有限公司 2018-11-16 CN disclosed
CN-105408328-A sGC stimulators IRONWOOD PHARMACEUTICALS INC 2016-03-16 CN disclosed