Cyclopentane

Cyclopentane

SCHEMBL22729196

C1CCCC1.NC(=O)NC(N)=O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.50
LMNA P02545 4/20 0.44
TSHR P16473 2/20 0.44
NFKB1 P19838 2/20 0.44
BLM P54132 2/20 0.44
PMP22 Q01453 2/20 0.44
CYP1A2 P05177 1/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
THPO P40225 1/20 0.44
CA2 P00918 1/20 0.44
CYP3A4 P08684 1/20 0.44
CA5A P35218 1/20 0.44
CA9 Q16790 1/20 0.44
EPHX1 P07099 5/20 0.39
ALDH1A1 P00352 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
OR51E2 Q9H255 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.34
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL1882975 1.00 CRBN (0.50) CRBNLMNATSHRNFKB1BLM
SCHEMBL11354262 1.00 CRBN (0.50) CRBNLMNATSHRNFKB1BLM
SCHEMBL15045 0.88
SCHEMBL27524722 0.88 CRBN (0.60) CRBNLMNATSHRNFKB1BLM
SCHEMBL27939070 0.88 CRBN (0.60) CRBNLMNATSHRNFKB1BLM
SCHEMBL27560286 0.88 CRBN (0.60) CRBNLMNATSHRNFKB1BLM
Water SCHEMBL7642577 0.84
SCHEMBL9475145 0.84
Hydrogen Peroxide SCHEMBL4232421 0.84
Ammonia Solution, Strong SCHEMBL9487082 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020245351-A1 CARBOCYCLIC NUCLEOSIDE ANALOGUE LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) 2020-12-10 WO disclosed
EP-3747872-A1 CARBOCYCLIC NUCLEOSIDE ANALOGUE Ludwig-Maximilians-Universität München (DE) 2020-12-09 EP disclosed