Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PDE1A | P54750 | 4/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.41 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729466 | 0.84 | NPBWR1 (0.43) | KDM4EALDH1A1PDE1APDE1BPDE1C | |
| SCHEMBL22729794 | 0.80 | MAPT (0.45) | KDM4ELMNAMAPTMCHR1 | |
| SCHEMBL22729427 | 0.78 | KCNH2 (0.44) | KDM4EALDH1A1LMNAMAPTMCHR1 | |
| SCHEMBL22729465 | 0.77 | MAPT (0.51) | KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL16052999 | 0.72 | CHRM1 (0.57) | CHRM1KDM4EALDH1A1LMNABRD4 | |
| SCHEMBL22729469 | 0.70 | KDM4E (0.46) | KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL14809708 | 0.70 | NPBWR1 (0.51) | CHRM1PTPN1KDM4EALDH1A1NPBWR1 | |
| SCHEMBL20746001 | 0.70 | NPBWR1 (0.51) | CHRM1PTPN1KDM4EALDH1A1LMNA | |
| SCHEMBL16053796 | 0.70 | CHRM1 (0.56) | CHRM1KDM4EALDH1A1LMNABRD4 | |
| SCHEMBL29049972 | 0.69 | PTPN1 (0.60) | CHRM1PTPN1ALDH1A1LMNANPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459325-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-10-04 | — | — | US | disclosed |
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-25 | — | — | US | disclosed |
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | GBA1, GBA2, GALC | CHRM1 2890/4885PTPN1 3094/4885KDM4E 1315/4885 |
| US-11459325-B2 | Heterocyclic compound | GBA1, GBA2, GALC | CHRM1 2901/4885PTPN1 3057/4885KDM4E 1270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.