Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 10/20 | 0.49 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729895 | 0.91 | LPAR1 (0.46) | LPAR1DHODHENPP2LPAR3 | |
| SCHEMBL22729896 | 0.90 | LPAR1 (0.51) | LPAR1ENPP2LPAR3CHRNB2CHRNB4 | |
| SCHEMBL16026395 | 0.90 | LPAR1 (0.55) | LPAR1ENPP2LPAR3 | |
| SCHEMBL16026397 | 0.90 | LPAR1 (0.55) | LPAR1ENPP2LPAR3 | |
| SCHEMBL22729880 | 0.90 | LPAR1 (0.43) | LPAR1DHODHLPAR3 | |
| SCHEMBL22729894 | 0.87 | LPAR1 (0.55) | LPAR1ENPP2LPAR3 | |
| SCHEMBL22729893 | 0.87 | LPAR1 (0.55) | LPAR1ENPP2LPAR3 | |
| SCHEMBL22729875 | 0.85 | LPAR1 (0.53) | LPAR1ENPP2LPAR3 | |
| SCHEMBL22729874 | 0.85 | LPAR1 (0.53) | LPAR1ENPP2LPAR3 | |
| SCHEMBL22729887 | 0.85 | LPAR1 (0.49) | LPAR1ENPP2LPAR3CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2988743-B1 | HETEROCYCLIC COMPOUNDS USEFUL IN THE TREATMENT OF DISEASE | EPIGEN BIOSCIENCES INC (US) | 2020-12-09 | — | — | EP | claimed |