Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 15/20 | 0.55 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | SMURF2 | Q9HAU4 | 1/20 | 0.35 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729894 | 1.00 | LPAR1 (0.55) | LPAR1LPAR3ENPP2LPAR2SMURF2 | |
| SCHEMBL16026397 | 0.95 | LPAR1 (0.55) | LPAR1LPAR3ENPP2LPAR2 | |
| SCHEMBL16026395 | 0.95 | LPAR1 (0.55) | LPAR1LPAR3ENPP2LPAR2 | |
| SCHEMBL22729874 | 0.94 | LPAR1 (0.53) | LPAR1LPAR3ENPP2LPAR2 | |
| SCHEMBL22729875 | 0.94 | LPAR1 (0.53) | LPAR1LPAR3ENPP2LPAR2 | |
| SCHEMBL22729884 | 0.92 | LPAR1 (0.55) | LPAR1LPAR3ENPP2LPAR2 | |
| SCHEMBL22729889 | 0.92 | LPAR1 (0.55) | LPAR1LPAR3ENPP2LPAR2 | |
| SCHEMBL22729892 | 0.87 | LPAR1 (0.49) | LPAR1LPAR3ENPP2 | |
| SCHEMBL22729896 | 0.86 | LPAR1 (0.51) | LPAR1LPAR3ENPP2LPAR2 | |
| SCHEMBL22729872 | 0.85 | LPAR1 (0.52) | LPAR1LPAR3ENPP2LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2988743-B1 | HETEROCYCLIC COMPOUNDS USEFUL IN THE TREATMENT OF DISEASE | EPIGEN BIOSCIENCES INC (US) | 2020-12-09 | — | — | EP | claimed |