Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | ARG2 | P78540 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24359721 | 1.00 | MEN1 (0.39) | MEN1FAAHKMT2ASOAT1MAPK1 | |
| SCHEMBL15602554 | 0.98 | ARG1 (0.37) | MEN1FAAHKMT2ASOAT1MAPK1 | |
| SCHEMBL4393706 | 0.91 | SLC6A2 (0.39) | MEN1FAAHKMT2AMAPK1KDM4E | |
| SCHEMBL16306470 | 0.85 | SOAT1 (0.38) | MEN1FAAHKMT2ASOAT1MAPK1 | |
| SCHEMBL3321078 | 0.84 | — | — | |
| SCHEMBL21386724 | 0.83 | SOAT1 (0.37) | MEN1FAAHKMT2ASOAT1MAPK1 | |
| SCHEMBL25453230 | 0.83 | PAOX (0.52) | MEN1FAAHKMT2AMAPK1PAOX | |
| SCHEMBL23729381 | 0.83 | PAOX (0.52) | MEN1FAAHKMT2AMAPK1PAOX | |
| SCHEMBL25453657 | 0.83 | PAOX (0.52) | MEN1FAAHKMT2AMAPK1PAOX | |
| SCHEMBL13311546 | 0.83 | PAOX (0.52) | MEN1FAAHKMT2AMAPK1PAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020237709-A1 | LONG-ACTING EXENATIDE DERIVATIVE AND SALT THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏诺泰澳赛诺生物制药股份有限公司 | 2020-12-03 | — | — | WO | disclosed |