SCHEMBL227322

SCHEMBL227322

CC(C)CC(OC(=O)c1ccccc1C(=O)O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.51
TSHR P16473 2/20 0.46
KDM4E B2RXH2 4/20 0.43
TAAR1 Q96RJ0 1/20 0.43
ALOX15 P16050 1/20 0.42
LMNA P02545 2/20 0.41
HPGD P15428 2/20 0.41
UTS2R Q9UKP6 3/20 0.40
HSD17B10 Q99714 2/20 0.39
TP53 P04637 1/20 0.39
KDM5A P29375 1/20 0.39
KDM4C Q9H3R0 1/20 0.39
KDM5B Q9UGL1 1/20 0.39
MYC P01106 1/20 0.38
NR4A1 P22736 1/20 0.38
KMT2A Q03164 1/20 0.38
GAA P10253 1/20 0.38
SCN1A P35498 1/20 0.37
SCN2A Q99250 1/20 0.37
SCN3A Q9NY46 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10477481 0.86 ALDH1A1 (0.55) ALDH1A1TSHRKDM4ETAAR1ALOX15
SCHEMBL226267 0.84 ALDH1A1 (0.54) ALDH1A1TSHRKDM4ETAAR1ALOX15
SCHEMBL7865741 0.84 ALDH1A1 (0.64) ALDH1A1TSHRKDM4EALOX15HSD17B10
SCHEMBL226438 0.83 ALDH1A1 (0.60) ALDH1A1TSHRKDM4ETAAR1ALOX15
SCHEMBL226494 0.83 ALDH1A1 (0.60) ALDH1A1TSHRKDM4ETAAR1ALOX15
SCHEMBL5155646 0.82 ALDH1A1 (0.58) ALDH1A1TSHRKDM4ETAAR1ALOX15
SCHEMBL3752645 0.81 ALDH1A1 (0.54) ALDH1A1KDM4ETAAR1ALOX15LMNA
SCHEMBL246586 0.80 ALDH1A1 (0.52) ALDH1A1TSHRKDM4ETAAR1ALOX15
SCHEMBL29389604 0.79 ALDH1A1 (0.63) ALDH1A1TSHRKDM4ETAAR1LMNA
SCHEMBL82574 0.79 ALDH1A1 (0.63) ALDH1A1TSHRKDM4ETAAR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2647668-B1 POLYESTER RESIN COMPOSITION AND MOLDED BODY OF SAME ADEKA CORP (JP) 2019-08-14 EP disclosed
EP-3075784-B1 PROCESS FOR PRODUCING MASTERBATCH ADEKA CORP (JP) 2018-10-03 EP disclosed
US-9890256-B2 Process for producing masterbatch ADEKA CORPORATION (JP) 2018-02-13 US disclosed
EP-2796487-B1 METHOD FOR PRODUCING MASTERBATCHES ADEKA CORP (JP) 2017-08-02 EP disclosed
EP-2407514-B1 REINFORCED POLYESTER RESIN COMPOSITION ADEKA CORP (JP) 2017-03-01 EP disclosed
US-9527966-B2 Method for producing masterbatches ADEKA CORPORATION (JP) 2016-12-27 US disclosed
US-20160347917-A1 PROCESS FOR PRODUCING MASTERBATCH ADEKA CORPORATION (JP) 2016-12-01 US disclosed
EP-3075784-A1 PROCESS FOR PRODUCING MASTERBATCH Adeka Corporation (JP) 2016-10-05 EP disclosed
CN-104053708-B The manufacture method of masterbatch ADEKA CORP. (JP) 2016-04-20 CN disclosed
US-20140350139-A1 METHOD FOR PRODUCING MASTERBATCHES ADEKA CORPORATION (JP) 2014-11-27 US disclosed
EP-2796487-A1 METHOD FOR PRODUCING MASTERBATCHES Adeka Corporation (JP) 2014-10-29 EP disclosed
CN-104053708-A Method for producing masterbatches ADEKA CORP 2014-09-17 CN disclosed
US-8829084-B2 Reinforced polyester resin composition ADEKA CORPORATION (JP) 2014-09-09 US disclosed
EP-2647668-A1 POLYESTER RESIN COMPOSITION AND MOLDED BODY OF SAME Adeka Corporation (JP) 2013-10-09 EP disclosed
US-20130253145-A1 POLYESTER RESIN COMPOSITION AND MOLDED BODY OF SAME ADEKA CORPORATION (JP) 2013-09-26 US disclosed
EP-2407514-A1 REINFORCED POLYESTER RESIN COMPOSITION Adeka Corporation (JP) 2012-01-18 EP disclosed
US-20120004363-A1 REINFORCED POLYESTER RESIN COMPOSITION ADEKA CORPORATION (JP) 2012-01-05 US disclosed