Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 3/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.47 |
| ▸ | RASGRP3 | Q8IV61 | 3/20 | 0.47 |
| ▸ | RASGRP1 | O95267 | 1/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22713034 | 0.89 | KMT2A (0.68) | MEN1KMT2AMAPTNPC1CASP3 | |
| SCHEMBL22713035 | 0.83 | MEN1 (0.60) | MEN1KMT2AMAPTNPC1CASP3 | |
| SCHEMBL23600586 | 0.82 | MEN1 (0.66) | MEN1KMT2AMAPTNPC1CASP3 | |
| SCHEMBL2134416 | 0.79 | MEN1 (0.61) | MEN1KMT2AMAPTNPC1CASP3 | |
| SCHEMBL8494188 | 0.79 | KMT2A (0.73) | MEN1KMT2AMAPTNPC1CASP3 | |
| SCHEMBL8494191 | 0.79 | KMT2A (0.73) | MEN1KMT2AMAPTNPC1CASP3 | |
| SCHEMBL14756766 | 0.78 | MAPT (0.71) | MEN1KMT2AMAPTNPC1CASP3 | |
| SCHEMBL2940762 | 0.78 | MEN1 (0.76) | MEN1KMT2AMAPTNPC1CASP3 | |
| SCHEMBL2940766 | 0.78 | MEN1 (0.76) | MEN1KMT2AMAPTNPC1CASP3 | |
| SCHEMBL15984842 | 0.77 | KMT2A (0.66) | MEN1KMT2AMAPTNPC1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210198235-A1 | DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF | AURANSA INC. | 2021-07-01 | — | — | US | disclosed |
| US-20200377510-A1 | DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF | AURANSA INC. | 2020-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200377510-A1 | DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF | SHARPIN, PIR, THPO | MEN1 1134/4885KMT2A 2446/4885MAPT 2707/4885 |
| US-20210198235-A1 | DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF | THPO, PIR, PAK6 | MEN1 1394/4885KMT2A 2507/4885MAPT 2532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.