Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.73 |
| ▸ | CDK1 | P06493 | 3/20 | 0.73 |
| ▸ | GSK3A | P49840 | 3/20 | 0.73 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.73 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.73 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.73 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.73 |
| ▸ | CDK2 | P24941 | 1/20 | 0.73 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.73 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.73 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.73 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.73 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.73 |
| ▸ | ROS1 | P08922 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23180940 | 0.87 | GSK3B (0.57) | GSK3BCDK1GSK3ACCNB2CCNB1 | |
| SCHEMBL19322385 | 0.87 | GSK3B (0.70) | GSK3BCDK1GSK3ACCNB2CCNB1 | |
| Laduviglusib SCHEMBL29359162 | 0.85 | GSK3B (1.00) | GSK3BCDK1GSK3ACCNB2CCNB1 | |
| Laduviglusib SCHEMBL29353709 | 0.85 | GSK3B (1.00) | GSK3BCDK1GSK3ACCNB2CCNB1 | |
| Laduviglusib SCHEMBL29351682 | 0.85 | GSK3B (1.00) | GSK3BCDK1GSK3ACCNB2CCNB1 | |
| Laduviglusib SCHEMBL151139 | 0.85 | GSK3B (1.00) | GSK3BCDK1GSK3ACCNB2CCNB1 | |
| Laduviglusib SCHEMBL29468026 | 0.84 | GSK3B (0.98) | GSK3BCDK1GSK3ACCNB2CCNB1 | |
| Laduviglusib SCHEMBL29361792 | 0.84 | GSK3B (0.98) | GSK3BCDK1GSK3ACCNB2CCNB1 | |
| Laduviglusib SCHEMBL30175104 | 0.84 | GSK3B (0.98) | GSK3BCDK1GSK3ACCNB2CCNB1 | |
| Laduviglusib SCHEMBL18301565 | 0.84 | GSK3B (0.98) | GSK3BCDK1GSK3ACCNB2CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3334820-B1 | INDUCED EXTENDED PLURIPOTENT STEM CELLS, METHODS OF MAKING AND USING | BEIHAO STEM CELL AND REGENERATIVE MEDICINE RES INSTITUTE CO LTD (CN) | 2024-05-15 | — | — | EP | claimed |
| US-20240060051-A1 | Method for Producing Naive Human IPS Cells From Somatic Cells | KYOTO UNIVERSITY (JP) | 2024-02-22 | — | — | US | disclosed |
| EP-4269571-A1 | METHOD FOR PRODUCING NAIVE HUMAN IPS CELLS FROM SOMATIC CELLS | Kyoto University (JP) | 2023-11-01 | — | — | EP | disclosed |
| US-20200385683-A1 | COMPOSITION AND METHOD FOR CULTURING ORGANOIDS | ORGANOIDSCIENCES, LTD. (KR) | 2020-12-10 | — | — | US | disclosed |
| CN-105658788-A | Method for preparing dopaminergic neurons | 武田药品工业株式会社 | 2016-06-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200385683-A1 | COMPOSITION AND METHOD FOR CULTURING ORGANOIDS | CNN2, FABP2, S100A4 | GSK3B 1197/4885CDK1 389/4885GSK3A 1365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.