Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 2/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 3/20 | 0.44 |
| ▸ | CTSS | P25774 | 6/20 | 0.44 |
| ▸ | CTSK | P43235 | 5/20 | 0.44 |
| ▸ | PCNA | P12004 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13919604 | 1.00 | ATM (0.53) | ATMABCB1ACACBITGB3ITGA2B | |
| SCHEMBL22774852 | 1.00 | ATM (0.53) | ATMABCB1ACACBITGB3ITGA2B | |
| SCHEMBL27848339 | 0.95 | ABCB1 (0.52) | ATMABCB1ACACBITGB3ITGA2B | |
| SCHEMBL20661670 | 0.89 | ATM (0.53) | ATMACACBITGB3ITGA2BAPP | |
| SCHEMBL4363556 | 0.89 | ATM (0.53) | ATMACACBITGB3ITGA2BAPP | |
| SCHEMBL24569507 | 0.87 | ATM (0.54) | ATMABCB1ACACBITGB3ITGA2B | |
| SCHEMBL21852417 | 0.87 | ACACB (0.51) | ATMACACBITGB3ITGA2BHDAC8 | |
| SCHEMBL7465898 | 0.87 | ATM (0.51) | ATMITGB3ITGA2BAPPCTSS | |
| SCHEMBL7465905 | 0.87 | ATM (0.51) | ATMITGB3ITGA2BAPPCTSS | |
| SCHEMBL21852432 | 0.87 | ACACB (0.51) | ATMACACBITGB3ITGA2BHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3759107-B1 | SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS WITH AN N-1 BRANCHED GROUP | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-12-04 | — | — | EP | disclosed |
| US-11370788-B2 | Substituted imidazo[4,5-c]quinoline compounds with an N-1 branched group | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2022-06-28 | — | — | US | disclosed |
| US-20220194935-A1 | PHENETHYL SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS WITH AN N-1 BRANCHED GROUP | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2022-06-23 | — | — | US | disclosed |
| CN-113906027-A | Phenethyl substituted imidazo [4,5-c ] quinoline compounds with N-1 branched groups | 3M创新有限公司 | 2022-01-07 | — | — | CN | disclosed |
| US-20200385379-A1 | SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS WITH AN N-1 BRANCHED GROUP | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2020-12-10 | — | — | US | disclosed |
| CN-101921268-B | 5-thiazole amide compound and biological applications | 中山大学肿瘤防治中心 | 2016-08-03 | — | — | CN | disclosed |
| CN-101921268-A | 5-thiazole amide compound and biology application thereof | UNIV SUN YAT SEN CANCER CT | 2010-12-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11370788-B2 | Substituted imidazo[4,5-c]quinoline compounds with an N-1 branched group | IFNG, IFNAR1, IRF3 | ATM 3385/4885ABCB1 2002/4885ACACB 2295/4885 |
| US-20220194935-A1 | PHENETHYL SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS WITH AN N-1 BRANCHED GROUP | IFNG, IFNAR1, IRF3 | ATM 3900/4885ABCB1 2217/4885ACACB 2152/4885 |
| US-20200385379-A1 | SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS WITH AN N-1 BRANCHED GROUP | IFNG, IFNAR1, IRF3 | ATM 3498/4885ABCB1 2701/4885ACACB 2131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.