Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 11/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 12/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22761556 | 1.00 | CYP3A4 (0.51) | CYP3A4CYP2D6CACNA1HCACNA1CMAPT | |
| SCHEMBL22761498 | 1.00 | CYP3A4 (0.51) | CYP3A4CYP2D6CACNA1HCACNA1CMAPT | |
| SCHEMBL2259283 | 1.00 | CYP3A4 (0.51) | CYP3A4CYP2D6CACNA1HCACNA1CMAPT | |
| SCHEMBL14428889 | 1.00 | CYP3A4 (0.51) | CYP3A4CYP2D6CACNA1HCACNA1CMAPT | |
| SCHEMBL22734707 | 0.88 | CYP3A4 (0.49) | CYP3A4CYP2D6CACNA1HCACNA1CMAPT | |
| SCHEMBL22761552 | 0.88 | CYP3A4 (0.49) | CYP3A4CYP2D6CACNA1HCACNA1CMAPT | |
| SCHEMBL9737738 | 0.86 | CYP3A4 (0.53) | CYP3A4CYP2D6CACNA1HCACNA1CMAPT | |
| SCHEMBL2259508 | 0.86 | CYP3A4 (0.53) | CYP3A4CYP2D6CACNA1HCACNA1CMAPT | |
| SCHEMBL8709648 | 0.86 | CYP3A4 (0.53) | CYP3A4CYP2D6CACNA1HCACNA1CMAPT | |
| Hydrochloric Acid SCHEMBL10798620 | 0.82 | CYP3A4 (0.49) | CYP3A4CYP2D6CACNA1HCACNA1CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11130750-B2 | Calcium channel inhibitors | CAVION, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-11130750-B2 | Calcium channel inhibitors | CAVION, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-20200385367-A1 | CALCIUM CHANNEL INHIBITORS | CAVION, INC. | 2020-12-10 | — | — | US | disclosed |
| US-20200385367-A1 | CALCIUM CHANNEL INHIBITORS | CAVION, INC. | 2020-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11130750-B2 | Calcium channel inhibitors | CACNA1F, ORAI1, CACNA1E | CYP3A4 2305/4885CYP2D6 3322/4885CACNA1H 12/4885 |
| US-20200385367-A1 | CALCIUM CHANNEL INHIBITORS | CACNA1F, ORAI1, CACNA1E | CYP3A4 2305/4885CYP2D6 3322/4885CACNA1H 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.