SCHEMBL22734862

SCHEMBL22734862

Cc1ccc(S(=O)(=O)N2Cc3c(C)ccc(C)c3C2)cc1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.59
HTT P42858 2/20 0.58
ALDH1A1 P00352 1/20 0.58
POLB P06746 1/20 0.58
MMP2 P08253 1/20 0.53
KMT2A Q03164 4/20 0.53
MEN1 O00255 3/20 0.53
GAA P10253 2/20 0.53
TSHR P16473 1/20 0.53
CYP2C19 P33261 1/20 0.53
LMNA P02545 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9693041 0.82 PKM (0.66) PKMHTTALDH1A1POLBMMP2
SCHEMBL12330052 0.82 PKM (0.66) PKMHTTALDH1A1POLBMMP2
SCHEMBL382551 0.82 PKM (0.56) PKMHTTALDH1A1POLBMMP2
SCHEMBL9185995 0.82 PKM (0.56) PKMHTTALDH1A1POLBMMP2
SCHEMBL11605844 0.81 PKM (0.63) PKMHTTALDH1A1POLBMMP2
SCHEMBL9186980 0.80 PKM (0.53) PKMHTTALDH1A1POLBMMP2
SCHEMBL11773546 0.79 PKM (0.61) PKMHTTALDH1A1POLBMMP2
SCHEMBL6407569 0.79 CD4 (0.64) PKMHTTALDH1A1POLBMMP2
SCHEMBL22208139 0.78 PKM (0.44) PKMHTTALDH1A1POLBMMP2
SCHEMBL10724066 0.78 PKM (0.88) PKMHTTALDH1A1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11260379-B2 Catalysts and methods for epoxide-based polymerizations CORNELL UNIVERSITY (US) 2022-03-01 US disclosed
US-20200384450-A1 CATALYSTS AND METHODS FOR EPOXIDE-BASED POLYMERIZATIONS CORNELL UNIVERSITY 2020-12-10 US disclosed
US-20200384450-A1 CATALYSTS AND METHODS FOR EPOXIDE-BASED POLYMERIZATIONS CORNELL UNIVERSITY 2020-12-10 US disclosed