Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FERMT2 | Q96AC1 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.48 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23340186 | 0.90 | FERMT2 (0.56) | FERMT2KDM4ELMNAHTTHSD17B10 | |
| SCHEMBL22734279 | 0.87 | FERMT2 (0.67) | FERMT2KDM4ELMNAHTTHSD17B10 | |
| SCHEMBL23904665 | 0.84 | CCR1 (0.66) | FERMT2KDM4ELMNAHTTHSD17B10 | |
| SCHEMBL22735859 | 0.84 | FERMT2 (0.63) | FERMT2KDM4ELMNAHTTHSD17B10 | |
| SCHEMBL17527085 | 0.83 | CDK1 (0.62) | FERMT2KDM4ELMNAHTTHSD17B10 | |
| SCHEMBL22735553 | 0.82 | FERMT2 (0.67) | FERMT2KDM4ELMNAHTTHSD17B10 | |
| SCHEMBL17527064 | 0.82 | CDK1 (0.61) | FERMT2KDM4ELMNAHTTHSD17B10 | |
| SCHEMBL19399297 | 0.80 | CDK1 (0.60) | FERMT2KDM4ELMNAHTTHSD17B10 | |
| SCHEMBL22734289 | 0.79 | CYP1A2 (0.57) | FERMT2KDM4ELMNAHTTHSD17B10 | |
| SCHEMBL22735629 | 0.79 | FERMT2 (0.56) | FERMT2KDM4ELMNAHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243037-A1 | BISAMINOQUINOLINES AND BISAMINOACRIDINES COMPOUNDS AND METHODS OF THEIR USE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2020-12-03 | — | — | WO | disclosed |