Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | FERMT2 | Q96AC1 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | CCR1 | P32246 | 1/20 | 0.55 |
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22734291 | 0.88 | HTR1A (0.58) | CYP1A2FERMT2LMNAKDM4EHTT | |
| SCHEMBL22734279 | 0.85 | FERMT2 (0.67) | CYP1A2FERMT2LMNAKDM4EHTT | |
| SCHEMBL18290380 | 0.84 | CYP1A2 (0.80) | CYP1A2FERMT2LMNAKDM4EHTT | |
| SCHEMBL23640947 | 0.83 | CYP1A2 (0.78) | CYP1A2FERMT2LMNAKDM4EHTT | |
| SCHEMBL15476608 | 0.83 | CYP1A2 (0.78) | CYP1A2FERMT2LMNAKDM4EHTT | |
| SCHEMBL22735859 | 0.82 | FERMT2 (0.63) | CYP1A2FERMT2LMNAKDM4EHTT | |
| SCHEMBL1860945 | 0.81 | CYP1A2 (0.70) | CYP1A2FERMT2LMNAKDM4EHTT | |
| SCHEMBL22734290 | 0.81 | CYP1A2 (0.74) | CYP1A2FERMT2LMNAKDM4EHTT | |
| SCHEMBL22735553 | 0.80 | FERMT2 (0.67) | CYP1A2FERMT2LMNAKDM4EHTT | |
| SCHEMBL22735631 | 0.79 | FERMT2 (0.52) | CYP1A2FERMT2LMNAKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243037-A1 | BISAMINOQUINOLINES AND BISAMINOACRIDINES COMPOUNDS AND METHODS OF THEIR USE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2020-12-03 | — | — | WO | disclosed |