Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31235807 | 0.98 | CARM1 (0.46) | CARM1PRMT6PRMT8ABCB1LTA4H | |
| SCHEMBL22498765 | 0.95 | CARM1 (0.46) | CARM1PRMT6PRMT8ABCB1LTA4H | |
| SCHEMBL12918861 | 0.84 | TSHR (0.45) | ABCB1OPRM1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL9302526 | 0.82 | CARM1 (0.68) | CARM1PRMT6PRMT8SMN1; SMN2TSHR | |
| SCHEMBL26310187 | 0.81 | HTT (0.45) | ABCB1OPRM1OPRD1OPRK1TSHR | |
| SCHEMBL11465304 | 0.81 | TSHR (0.54) | ABCB1LTA4HOPRM1OPRD1OPRK1 | |
| SCHEMBL24178220 | 0.80 | CALM1 (0.44) | ABCB1SMN1; SMN2CALM1CAMKK2TSHR | |
| SCHEMBL21043434 | 0.80 | CALM1 (0.44) | ABCB1SMN1; SMN2CALM1CAMKK2TSHR | |
| SCHEMBL31156713 | 0.80 | HTT (0.51) | ABCB1OPRM1OPRD1OPRK1TSHR | |
| SCHEMBL24440540 | 0.80 | HTT (0.51) | ABCB1OPRM1OPRD1OPRK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243037-A1 | BISAMINOQUINOLINES AND BISAMINOACRIDINES COMPOUNDS AND METHODS OF THEIR USE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2020-12-03 | — | — | WO | disclosed |