Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.32 |
| ▸ | CDK9 | P50750 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.30 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29480666 | 1.00 | HDAC4 (0.34) | HDAC4CCNT1CDK9JAK1JAK2 | |
| SCHEMBL22735730 | 0.92 | MAP3K12 (0.34) | HDAC4CCNT1CDK9JAK1JAK2 | |
| SCHEMBL29567334 | 0.92 | HDAC4 (0.33) | HDAC4CCNT1CDK9JAK1 | |
| SCHEMBL29480650 | 0.92 | MAP3K12 (0.34) | HDAC4CCNT1CDK9JAK1JAK2 | |
| SCHEMBL22736022 | 0.92 | HDAC4 (0.33) | HDAC4CCNT1CDK9JAK1 | |
| SCHEMBL22736502 | 0.90 | AURKA (0.33) | HDAC4 | |
| SCHEMBL29480499 | 0.90 | AURKA (0.33) | HDAC4 | |
| SCHEMBL29480597 | 0.88 | HDAC4 (0.34) | HDAC4JAK1JAK2 | |
| SCHEMBL22736027 | 0.88 | HDAC4 (0.34) | HDAC4JAK1JAK2 | |
| SCHEMBL22735866 | 0.88 | KDM4A (0.33) | HDAC4CDK9GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020240586-A1 | NOVEL COMPOUNDS FOR INHIBITION OF JANUS KINASE 1 | MANKIND PHARMA LTD. (IN) | 2020-12-03 | — | — | WO | disclosed |