Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.52 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL1255194 | 1.00 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL4188267 | 1.00 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL524377 | 1.00 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL4326067 | 1.00 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL14691492 | 1.00 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL11068071 | 0.98 | TSHR (0.58) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL18813683 | 0.96 | TSHR (0.56) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL15577101 | 0.96 | TSHR (0.56) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL28770491 | 0.94 | TSHR (0.54) | TSHRDAONAPRTSRD5A2CES1 | |
| Terephthalic Acid SCHEMBL855281 | 0.91 | TSHR (0.57) | TSHRDAONAPRTSRD5A2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3062 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122078014-A | PVB intermediate film with binary compound plasticizing gradient structure, preparation method thereof and laminated glass | — | 2026-05-26 | — | — | CN | claimed |
| US-20260109795-A1 | HIGH REFRACTIVE INDEX POLYVINYL ACETAL RESINS MODIFIED WITH CYCLIC ALDEHYDES | EASTMAN CHEMICAL COMPANY (US) | 2026-04-23 | — | — | US | claimed |
| US-20260048001-A1 | SKINCARE COMPOSITION CONTAINING CASHEW APPLE EXTRACT | R & D GLOBAL CONSULTANTS PVT LTD (IN) | 2026-02-19 | — | — | US | claimed |
| US-12551458-B2 | Topical pharmaceutical composition containing phospholipids | EGIS GYÓGYSZERGYÁR ZRT. (HU) | 2026-02-17 | — | — | US | claimed |
| US-20260020558-A1 | NEW AGROCHEMICAL FORMULATIONS | BASF SE (DE) | 2026-01-22 | — | — | US | claimed |
| WO-2025233453-A1 | NEW AGROCHEMICAL FORMULATIONS | BASF SE (DE) | 2025-11-13 | — | — | WO | claimed |
| EP-3021830-B2 | COMPOSITIONS AND METHODS FOR TREATING HAIR | OREAL (FR) | 2025-09-03 | — | — | EP | claimed |
| EP-4598999-A1 | HIGH REFRACTIVE INDEX POLYVINYL ACETAL RESINS MODIFIED WITH CYCLIC ALDEHYDES | Eastman Chemical Company (US) | 2025-08-13 | — | — | EP | claimed |
| WO-2025137392-A1 | CONDITIONER COMPOSITIONS, CLEANSER COMPOSITIONS AND METHODS OF USING THE SAME | K18, INC. (US) | 2025-06-26 | — | — | WO | claimed |
| US-20250197609-A1 | ECOFRIENDLY, BIODEGRADABLE BIOLOGICAL POLYSACCHARIDE COMPOSITION FOR PACKAGING MATERIALS | BLUE EVOLUTION, INC. (US) | 2025-06-19 | — | — | US | claimed |
| US-5284907-A | Emulsion polymerization of an unsaturated compound having a moiety of a rubber additive and a conjugated diene using an ionic surfactant and a plasticizer functioning as the solvent and dispersant | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1994-02-08 | — | — | US | claimed |
| US-5232956-A | Of a polyol and diphenylmethane diisocyanate, and a phthalate, benzoate or phosphate ester plasticizer | MONSANTO COMPANY (US) | 1993-08-03 | — | — | US | claimed |
| WO-1993003090-A1 | FLEXIBLE WATER-BLOWN POLYURETHANE FOAMS | MONSANTO COMPANY (US) | 1993-02-18 | — | — | WO | claimed |
| US-5145671-A | As plasticizers | REVLON, INC. (US) | 1992-09-08 | — | — | US | claimed |
| EP-0470040-A1 | Process for the preparation of a rubber having polymer bound functionality | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-02-05 | — | — | EP | claimed |
| EP-0470042-A1 | Process for the preparation of a masterbatch rubber having polymer bound functionality | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-02-05 | — | — | EP | claimed |
| EP-0455373-A1 | Nail enamels containing glyceryl triesters | Revlon Consumer Products Corporation (US) | 1991-11-06 | — | — | EP | claimed |
| EP-0161118-B1 | FLEXIBLE POLYVINYLIDENE FLUORIDE COMPOSITIONS, AND THEIR USE, ESPECIALLY IN MAKING FLEXIBLE TUBES | Institut Français du Pétrole (FR) | 1988-09-14 | — | — | EP | claimed |
| US-4699940-A | POLAR SOLVENTS, PLASTICIZERS, ELASTOMERS | PROTECTIVE TREATMENTS, INC. (US) | 1987-10-13 | — | — | US | claimed |
| US-4584215-A | INCORPORATING ESTER IN POLYMER COMPOSITION | INSTITUT FRANCAIS DU PETROLE (FR) | 1986-04-22 | — | — | US | claimed |