Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.52 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL1255194 | 1.00 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL4188267 | 1.00 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL4326067 | 1.00 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL14691492 | 1.00 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL227396 | 1.00 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL11068071 | 0.98 | TSHR (0.58) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL18813683 | 0.96 | TSHR (0.56) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL15577101 | 0.96 | TSHR (0.56) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL28770491 | 0.94 | TSHR (0.54) | TSHRDAONAPRTSRD5A2CES1 | |
| Terephthalic Acid SCHEMBL855281 | 0.91 | TSHR (0.57) | TSHRDAONAPRTSRD5A2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118046691-A | Acrylic acid type water-soluble pattern film, preparation method and application thereof | 孙琇芳 | 2024-05-17 | — | — | CN | claimed |
| CN-114410165-A | Difficult-to-fall colored decorative paint | 陕西亮业科建设工程集团有限公司 | 2022-04-29 | — | — | CN | claimed |
| CN-114273857-A | Preparation process of clutch booster | 绍兴力欣液压件有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-109180843-B | Non-phthalate compounds as electron donors for polyolefin catalysts | 美国台塑公司 | 2022-03-01 | — | — | CN | claimed |
| CN-108463209-B | Nail compositions with end-capped oligomers | 露华浓消费品公司 | 2021-09-17 | — | — | CN | claimed |
| CN-106883808-B | Adhesive, preparation method thereof and electrophoretic display | 广州奥翼电子科技股份有限公司 | 2021-02-12 | — | — | CN | claimed |
| CN-106967379-B | Electrophoretic display device, adhesive and preparation method thereof | 广州奥翼电子科技股份有限公司 | 2020-12-08 | — | — | CN | claimed |
| CN-110396330-A | A kind of antifreeze emulsion paint | JIANGSU SHUNCHANG NEW BUILDING MAT CO LTD | 2019-11-01 | — | — | CN | claimed |
| US-20160194455-A1 | Silicone Elastomer Gels and Related Hydrosilylation Processes | ALZO INT INC (US) | 2016-07-07 | — | — | US | claimed |
| CN-105400331-A | Priming paint | CHANGSU WANXIANG PAINT CO LTD | 2016-03-16 | — | — | CN | claimed |
| EP-1389084-A1 | COSMETIC FILMS | Coty Inc. (US) | 2004-02-18 | — | — | EP | claimed |
| US-20030147838-A1 | Cosmetic films | OPI PRODUCTS, INC. | 2003-08-07 | — | — | US | claimed |
| US-20030124154-A1 | Cosmetic films | OPI PRODUCTS, INC. | 2003-07-03 | — | — | US | claimed |
| EP-1292274-A2 | METHOD OF MAKING ENHANCED EFFICACY ANTIPERSPIRANT ACTIVES | Colgate-Palmolive Company (US) | 2003-03-19 | — | — | EP | claimed |
| US-20030003069-A1 | Multiple phase foaming personal cleansing products | ALZO INTERNATIONAL, INC. | 2003-01-02 | — | — | US | claimed |
| WO-2002102329-A1 | COSMETIC FILMS | COTY INC. (US) | 2002-12-27 | — | — | WO | claimed |
| WO-2002064668-A1 | ANTIMICROBIAL SUPERFINISH AND METHOD OF MAKING | MICROBAN PRODUCTS COMPANY (US) | 2002-08-22 | — | — | WO | claimed |
| WO-2001097768-A2 | METHOD OF MAKING ENHANCED EFFICACY ANTIPERSPIRANT ACTIVES | COLGATE-PALMOLIVE COMPANY (US) | 2001-12-27 | — | — | WO | claimed |
| US-5948268-A | DISSOLVING IN WATER TO BE TREATED A POLYMER FORMED FROM WATER SOLUBLE MONOMER UNITS COMPRISING A (POLY)ALKYLENE OXIDE END CAPPED WITH AN ADDITION POLYMERIZABLE GROUP AT ONE END AND AN INTENSELY FLUORESCENT GROUP AT OTHER | NIPPON SHOKUBAI CO., LTD. (JP) | 1999-09-07 | — | — | US | claimed |
| US-4656214-A | DIESTERS | EXXON RESEARCH & ENGINEERING CO. (US) | 1987-04-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194455-A1 | Silicone Elastomer Gels and Related Hydrosilylation Processes | ITCH, MMS19, STS | TSHR 3868/4885DAO 3360/4885NAPRT 4509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.