Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22743050 | 0.75 | CHEK1 (0.45) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL5526838 | 0.74 | MAPT (0.42) | KDM4EALDH1A1MAPTCYP3A4SCN10A | |
| SCHEMBL4559086 | 0.74 | HRH4 (0.36) | KDM4EALDH1A1MAPTQPCT | |
| SCHEMBL8013060 | 0.70 | PRKCI (0.53) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL1454701 | 0.69 | PARP1 (0.63) | ALDH1A1SMN1; SMN2ALOX15FLT1KDR | |
| SCHEMBL28268757 | 0.68 | RAB9A (0.40) | KDM4EALDH1A1HSD17B10GAANPC1 | |
| SCHEMBL10122186 | 0.68 | NPC1 (0.43) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL11322091 | 0.68 | OGA (0.40) | KDM4EALDH1A1HSD17B10GAANPC1 | |
| SCHEMBL25722773 | 0.68 | PARP1 (0.31) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL22699769 | 0.68 | KDM4E (0.41) | KDM4EALDH1A1HSD17B10GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243178-A1 | HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS | ANGEX PHARMACEUTICAL, INC. (US) | 2020-12-03 | — | — | WO | disclosed |