Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22743562 | 0.77 | PDPK1 (0.33) | PDPK1HCAR2 | |
| SCHEMBL22744355 | 0.76 | DYRK1A (0.31) | — | |
| SCHEMBL22743477 | 0.68 | TNKS (0.32) | PDPK1 | |
| SCHEMBL19902649 | 0.66 | PARP1 (0.42) | — | |
| SCHEMBL22743476 | 0.66 | PARP1 (0.45) | — | |
| SCHEMBL19152895 | 0.63 | WNT3A (0.38) | PDPK1 | |
| SCHEMBL18237905 | 0.63 | WNT3A (0.38) | PDPK1 | |
| SCHEMBL22743690 | 0.62 | PDPK1 (0.31) | PDPK1 | |
| SCHEMBL19152937 | 0.61 | PDPK1 (0.33) | PDPK1 | |
| SCHEMBL19152636 | 0.61 | PDPK1 (0.33) | PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239076-A1 | PYRIDAZINONE DERIVATIVES AS THYROXINE RECEPTOR-Β AGONISTS AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2020-12-03 | — | — | WO | disclosed |