Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27634673 | 0.77 | CYP1A2 (0.42) | KDM4ELMNACYP1A2USP2MEN1 | |
| SCHEMBL21335574 | 0.67 | TP53 (0.48) | KDM4ECYP1A2USP2MEN1HPGD | |
| SCHEMBL20786877 | 0.67 | NPSR1 (0.40) | KDM4ELMNACYP1A2USP2MEN1 | |
| SCHEMBL1103817 | 0.66 | ALDH1A1 (0.40) | KDM4ECYP1A2USP2MEN1HPGD | |
| SCHEMBL26558903 | 0.64 | CYP1A2 (0.39) | LMNACYP1A2ALDH1A1ADORA2BPDE4B | |
| SCHEMBL18927854 | 0.64 | CYP1A2 (0.44) | KDM4ELMNACYP1A2HPGDALDH1A1 | |
| SCHEMBL10289838 | 0.64 | HTT (0.33) | — | |
| SCHEMBL21032897 | 0.64 | PRMT5 (0.42) | KDM4ECYP1A2MEN1HPGDKMT2A | |
| SCHEMBL15228318 | 0.63 | CYP1A2 (0.40) | KDM4ELMNACYP1A2MEN1KMT2A | |
| SCHEMBL12652837 | 0.63 | CSNK2A1 (0.39) | KDM4ELMNACYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3777979-A1 | ANTI-INFLAMMATORY COMPOUND AND PREPARATION AND USE THEREOF | Vivavision Biotech, Inc. (CN) | 2021-02-17 | — | — | EP | disclosed |
| US-20200377460-A1 | ANTI-INFLAMMATORY COMPOUND, AND PREPARATION AND USE THEREOF | VIVAVISION BIOTECH, INC. (CN) | 2020-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200377460-A1 | ANTI-INFLAMMATORY COMPOUND, AND PREPARATION AND USE THEREOF | PDE4B, PDE4A, PDE7A | KDM4E 468/4885LMNA 3960/4885CYP1A2 605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.