Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14127790 | 1.00 | KCNH2 (0.48) | KCNH2RAB9AGBA1NPC1SMN1; SMN2 | |
| SCHEMBL9082300 | 1.00 | KCNH2 (0.48) | KCNH2RAB9AGBA1NPC1SMN1; SMN2 | |
| SCHEMBL28171815 | 1.00 | KCNH2 (0.48) | KCNH2RAB9AGBA1NPC1SMN1; SMN2 | |
| SCHEMBL9083017 | 1.00 | KCNH2 (0.48) | KCNH2RAB9AGBA1NPC1SMN1; SMN2 | |
| SCHEMBL2358386 | 0.98 | GBA1 (0.47) | KCNH2RAB9AGBA1NPC1SMN1; SMN2 | |
| SCHEMBL10461384 | 0.92 | GBA1 (0.48) | KCNH2RAB9AGBA1NPC1SMN1; SMN2 | |
| SCHEMBL9083483 | 0.91 | RAB9A (0.42) | KCNH2RAB9AGBA1NPC1SMN1; SMN2 | |
| SCHEMBL31729646 | 0.84 | GBA1 (0.52) | RAB9AGBA1NPC1SMN1; SMN2NFKB1 | |
| SCHEMBL3231706 | 0.84 | GBA1 (0.52) | RAB9AGBA1NPC1SMN1; SMN2NFKB1 | |
| SCHEMBL4764131 | 0.80 | GBA1 (0.41) | RAB9AGBA1NPC1SMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020245297-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ALMIRALL, S.A. (ES) | 2020-12-10 | — | — | WO | disclosed |