Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.36 |
| ▸ | DRD3 | P35462 | 8/20 | 0.36 |
| ▸ | DRD4 | P21917 | 5/20 | 0.36 |
| ▸ | HTR1D | P28221 | 3/20 | 0.35 |
| ▸ | DRD1 | P21728 | 3/20 | 0.34 |
| ▸ | DRD5 | P21918 | 3/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22748394 | 1.00 | DRD2 (0.36) | DRD2DRD3DRD4HTR1DDRD1 | |
| SCHEMBL10512980 | 0.99 | DRD2 (0.36) | DRD2DRD3DRD4HTR1DDRD1 | |
| SCHEMBL10015000 | 0.90 | DRD2 (0.38) | DRD2DRD3DRD4HTR1DDRD1 | |
| SCHEMBL2178698 | 0.84 | DRD2 (0.37) | DRD2DRD3DRD4HTR1DDRD1 | |
| SCHEMBL18069445 | 0.80 | DRD2 (0.33) | DRD2DRD3DRD4HTR1DDRD1 | |
| SCHEMBL19449967 | 0.80 | DRD2 (0.34) | DRD2DRD3DRD4HTR1DDRD1 | |
| SCHEMBL25403854 | 0.78 | SLC18A3 (0.32) | DRD2DRD3HTR1D | |
| SCHEMBL25172071 | 0.78 | DRD2 (0.40) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL26146514 | 0.78 | DRD2 (0.40) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL12811147 | 0.78 | DRD2 (0.33) | DRD2DRD3DRD4HTR1DDRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020245297-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ALMIRALL, S.A. (ES) | 2020-12-10 | — | — | WO | disclosed |