Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5539632 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPK1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL5543126 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MAPK1SMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL15667399 | 0.75 | EHMT2 (0.48) | ALDH1A1MAPTHPGDNPC1RAB9A | |
| SCHEMBL23056401 | 0.74 | ALDH1A1 (0.40) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| SCHEMBL5543712 | 0.74 | ALDH1A1 (0.50) | ALDH1A1MAPK1SMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL5536599 | 0.73 | HDAC1 (0.49) | ALDH1A1MAPK1SMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL5544648 | 0.73 | HDAC1 (0.49) | ALDH1A1MAPK1SMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL12317734 | 0.71 | ALDH1A1 (0.46) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| SCHEMBL10700265 | 0.71 | SMN1; SMN2 (0.55) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| SCHEMBL5540726 | 0.68 | ALDH1A1 (0.46) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322804-A1 | REAGENTS FOR REVERSIBLY PROTECTING BIOLOGICAL MOLECULES | bioMérieux (FR) | 2023-10-12 | — | — | US | disclosed |
| EP-3980057-A1 | METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF | Institut Curie (FR) | 2022-04-13 | — | — | EP | disclosed |
| WO-2020245321-A1 | METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STxB) MONOMERS AND OLIGOMERS, AND USES THEREOF | INSTITUT CURIE (FR) | 2020-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322804-A1 | REAGENTS FOR REVERSIBLY PROTECTING BIOLOGICAL MOLECULES | AZI2, TPMT, CA12 | ALDH1A1 230/4885MAPK1 4571/4885SMN1; SMN2 4180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.