Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.40 |
| ▸ | HMGCR | P04035 | 2/20 | 0.40 |
| ▸ | RARB | P10826 | 2/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22748696 | 1.00 | GPR84 (0.54) | GPR84FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL22748304 | 1.00 | GPR84 (0.54) | GPR84FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL22748622 | 1.00 | GPR84 (0.54) | GPR84FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL22748441 | 1.00 | GPR84 (0.54) | GPR84FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL22748373 | 0.85 | GPR84 (0.50) | GPR84FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL22748766 | 0.85 | GPR84 (0.50) | GPR84FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL22748419 | 0.85 | GPR84 (0.50) | GPR84FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL22748449 | 0.85 | GPR84 (0.50) | GPR84FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL22748342 | 0.85 | GPR84 (0.50) | GPR84FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL22748760 | 0.81 | GPR84 (0.46) | GPR84FFAR1FFAR4MMP2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020245297-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ALMIRALL, S.A. (ES) | 2020-12-10 | — | — | WO | disclosed |