Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 7/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688 | 0.97 | — | — | |
| SCHEMBL7396758 | 0.97 | ALDH1A1 (0.62) | ALDH1A1PTGS1MAPTSLC7A5DPP4 | |
| SCHEMBL1183636 | 0.97 | — | — | |
| SCHEMBL6433 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL29448819 | 0.94 | ALDH1A1 (0.59) | ALDH1A1PTGS1MAPTSLC7A5DPP4 | |
| Hydrochloric Acid SCHEMBL2852111 | 0.94 | ALDH1A1 (0.59) | ALDH1A1PTGS1MAPTSLC7A5DPP4 | |
| Hydrochloric Acid SCHEMBL158225 | 0.94 | ALDH1A1 (0.59) | ALDH1A1PTGS1MAPTSLC7A5DPP4 | |
| Ammonia Solution, Strong SCHEMBL28108684 | 0.94 | ALDH1A1 (0.59) | ALDH1A1PTGS1MAPTSLC7A5DPP4 | |
| Acetic Acid SCHEMBL28270661 | 0.92 | ALDH1A1 (0.56) | ALDH1A1PTGS1MAPTSLC7A5DPP4 | |
| Alanine SCHEMBL28074362 | 0.89 | ALDH1A1 (0.54) | ALDH1A1PTGS1MAPTSLC7A5DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12441762-B2 | Hepatitis c virus NS3/4A protease inhibitors | UNIVERSITY OF MASSACHUSETTS (US) | 2025-10-14 | — | — | US | disclosed |
| US-20220227806-A1 | HEPATITIS C VIRUS NS3/4A PROTEASE INHIBITORS | UNIV MASSACHUSETTS (US) | 2022-07-21 | — | — | US | disclosed |
| WO-2020247736-A1 | HEPATITIS C VIRUS NS3/4A PROTEASE INHIBITORS | UNIVERSITY OF MASSACHUSETTS (US) | 2020-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12441762-B2 | Hepatitis c virus NS3/4A protease inhibitors | HAVCR2, CTSC, DPP4 | ALDH1A1 1277/4885PTGS1 1773/4885MAPT 2763/4885 |
| US-20220227806-A1 | HEPATITIS C VIRUS NS3/4A PROTEASE INHIBITORS | HAVCR2, CTSC, DPP4 | ALDH1A1 1277/4885PTGS1 1773/4885MAPT 2763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.