Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | HCK | P08631 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12072478 | 0.85 | HSP90AB1 (0.46) | HSP90AA1HSP90AB1 | |
| SCHEMBL2302499 | 0.81 | CDK2 (0.41) | HSP90AA1HSP90AB1CDK2 | |
| SCHEMBL5142678 | 0.80 | ADORA2A (0.38) | HSP90AA1HSP90AB1ADORA2AADORA1CYP2C19 | |
| SCHEMBL4796358 | 0.79 | ADORA2A (0.39) | ADORA2AADORA1CYP2C19CDK1CCNB1 | |
| SCHEMBL29124866 | 0.76 | CDK1 (0.51) | HSP90AA1HSP90AB1ADORA2AADORA1CDK1 | |
| SCHEMBL14002358 | 0.76 | ADORA2A (0.59) | HSP90AA1HSP90AB1ADORA2AADORA1ADORA3 | |
| SCHEMBL14002330 | 0.76 | ADORA2A (0.62) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL17260460 | 0.74 | GSK3B (0.56) | PIK3CAPIK3CDABL1EGFRHCK | |
| SCHEMBL8496416 | 0.71 | BCHE (0.36) | HSP90AA1HSP90AB1 | |
| SCHEMBL3002833 | 0.70 | ALDH1A1 (0.34) | HSP90AA1HSP90AB1PIK3CDADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536724-B2 | PROCESS FOR PREPARING ENTECAVIR AND ITS INTERMEDIATES | SCINOPHARM TAIWAN LTD (TW) | 2019-10-23 | — | — | EP | disclosed |
| EP-2536724-B1 | PROCESS FOR PREPARING ENTECAVIR AND ITS INTERMEDIATES | SCINOPHARM TAIWAN LTD (TW) | 2016-11-23 | — | — | EP | disclosed |
| CN-102741254-B | Process for preparing entecavir and intermediates thereof | 台湾神隆股份有限公司 | 2016-08-10 | — | — | CN | disclosed |
| US-8481728-B2 | Process for preparing entecavir and its intermediates | SCINOPHARM TAIWAN, LTD. (TW) | 2013-07-09 | — | — | US | disclosed |
| US-8481728-B2 | Process for preparing entecavir and its intermediates | SCINOPHARM TAIWAN, LTD. (TW) | 2013-07-09 | — | — | US | disclosed |
| US-8481728-B2 | Process for preparing entecavir and its intermediates | SCINOPHARM TAIWAN, LTD. (TW) | 2013-07-09 | — | — | US | disclosed |
| EP-2536724-A1 | PROCESS FOR PREPARING ENTECAVIR AND ITS INTERMEDIATES | ScinoPharm Taiwan, Ltd. (TW) | 2012-12-26 | — | — | EP | disclosed |
| CN-102741254-A | Process for preparing entecavir and intermediates thereof | SCINOPHARM TAIWAN LTD | 2012-10-17 | — | — | CN | disclosed |
| WO-2011102806-A1 | PROCESS FOR PREPARING ENTECAVIR AND ITS INTERMEDIATES | SCINOPHARM TAIWAN LTD (TW) | 2011-08-25 | — | — | WO | disclosed |
| US-20110201809-A1 | Process for Preparing Entecavir and its Intermediates | SCINOPHARM TAIWAN, LTD. | 2011-08-18 | — | — | US | disclosed |
| US-20110201809-A1 | Process for Preparing Entecavir and its Intermediates | SCINOPHARM TAIWAN, LTD. | 2011-08-18 | — | — | US | disclosed |
| US-20110201809-A1 | Process for Preparing Entecavir and its Intermediates | SCINOPHARM TAIWAN, LTD. | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201809-A1 | Process for Preparing Entecavir and its Intermediates | ENTPD5, TYMS, TYMP | HSP90AA1 3838/4885HSP90AB1 3879/4885PIK3CA 772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.