SCHEMBL227502

SCHEMBL227502

OC1CCc2cc(Br)ccc21

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 2/20 0.45
CAMK2A Q9UQM7 1/20 0.45
PGR P06401 1/20 0.42
GFRA3 O60609 1/20 0.41
RET P07949 1/20 0.41
KDM1A O60341 4/20 0.40
SLC6A4 P31645 4/20 0.37
SLC6A2 P23975 1/20 0.37
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
TRPV1 Q8NER1 1/20 0.36
PNMT P11086 1/20 0.36
ASIC3 Q9UHC3 1/20 0.36
SRD5A2 P31213 1/20 0.36
PYGL P06737 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14437215 1.00 SRD5A1 (0.45) SRD5A1CAMK2APGRGFRA3RET
SCHEMBL2435536 1.00 SRD5A1 (0.45) SRD5A1CAMK2APGRGFRA3RET
SCHEMBL3202300 1.00 SRD5A1 (0.45) SRD5A1CAMK2APGRGFRA3RET
SCHEMBL31650212 0.89 CAMK2A (0.50) SRD5A1CAMK2APGRKDM1ASLC6A4
SCHEMBL7679993 0.89 CAMK2A (0.50) SRD5A1CAMK2APGRKDM1ASLC6A4
SCHEMBL16794356 0.87 CAMK2A (0.49) SRD5A1CAMK2APGRKDM1ASLC6A4
SCHEMBL9276752 0.84 HTR2A (0.46) SRD5A1CAMK2AKDM1AHTR2AHTR2C
SCHEMBL1576024 0.84 HTR2A (0.46) SRD5A1CAMK2AKDM1AHTR2AHTR2C
SCHEMBL3638981 0.84 HTR2A (0.46) SRD5A1CAMK2AKDM1AHTR2AHTR2C
SCHEMBL27887272 0.78 KDM1A (0.42) SRD5A1CAMK2AKDM1ASLC6A4SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743174-A1 MODULATORS OF CALCITONIN RECEPTOR AND/OR AMYLIN RECEPTOR ACTIVITY Aconcagua Bio, Inc. (US) 2026-05-20 EP disclosed
US-12624003-B2 Carboxylic acid containing indanyl compounds for the treatment of neurodegenerative diseases CELGENE CORPORATION (US) 2026-05-12 US disclosed
EP-4267117-B1 CARBOXYLIC ACID CONTAINING INDANYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES CELGENE CORP (US) 2026-04-08 EP disclosed
EP-3950676-B1 PREPARATION METHOD FOR AMIDE COMPOUNDS AND APPLICATION THEREOF IN FIELD OF MEDICINE SHANGHAI SYNERGY PHARMACEUTICAL SCIENCES CO LTD (CN) 2026-04-08 EP disclosed
US-12595267-B2 Preparation method for amide compound and application thereof in field of medicine SHANGHAI SYNERGY PHARMACEUTICAL SCIENCES CO., LTD. (CN) 2026-04-07 US disclosed
US-12570655-B2 Cysteine covalent modifiers of AKT1 and uses thereof TERREMOTO BIOSCIENCES, INC. (US) 2026-03-10 US disclosed
WO-2025081045-A9 CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. (US) 2025-12-26 WO disclosed
US-20250320212-A1 TRICYCLIC UREA COMPOUNDS AS JAK2 V617F INHIBITORS INCYTE CORP (US) 2025-10-16 US disclosed
EP-4620469-A2 TRICYCLIC UREA COMPOUNDS AS JAK2 V617F INHIBITORS Incyte Corporation (US) 2025-09-24 EP disclosed
US-20250289819-A1 CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. 2025-09-18 US disclosed
US-5338740-A Angiotensin II receptor antagonists PFIZER INC. (US) 1994-08-16 US disclosed
EP-0589484-A1 1,2-Ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same TOYAMA CHEMICAL CO., LTD. (JP) 1994-03-30 EP disclosed
EP-0587194-A1 2-(Heterocycloalkoxy)-1-(subst.-phenyl)-ethanol derivatives as cerebral function improving agents TOYAMA CHEMICAL CO., LTD. (JP) 1994-03-16 EP disclosed
EP-0587193-A1 1,2-Ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same TOYAMA CHEMICAL CO., LTD. (JP) 1994-03-16 EP disclosed
US-5280032-A 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same TOYAMA CHEMICAL CO., LTD. (JP) 1994-01-18 US disclosed
EP-0357742-B1 NEW PYRETHRINOID ESTERS CARRYING AN INDANYL RING, PREPARATION METHOD AND APPLICATION AS PESTICIDES ROUSSEL-UCLAF (FR) 1993-06-09 EP disclosed
US-5180741-A Insecticides ROUSSEL UCLAF (FR) 1993-01-19 US disclosed
EP-0383281-A1 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same TOYAMA CHEMICAL CO., LTD. (JP) 1990-08-22 EP disclosed
EP-0357742-A1 NEW PYRETHRINOID ESTERS CARRYING AN INDANYL RING, PREPARATION METHOD AND APPLICATION AS PESTICIDES. ROUSSEL UCLAF (FR) 1990-03-14 EP disclosed
WO-1989008096-A1 NEW PYRETHRINOID ESTERS CARRYING AN INDANYL RING, PREPARATION METHOD AND APPLICATION AS PESTICIDES ROUSSEL-UCLAF (FR) 1989-09-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250320212-A1 TRICYCLIC UREA COMPOUNDS AS JAK2 V617F INHIBITORS JAK2, JAK1, JAK3 SRD5A1 4502/4885CAMK2A 1353/4885PGR 1469/4885
US-12570655-B2 Cysteine covalent modifiers of AKT1 and uses thereof AKT1, AKT2, AKT3 SRD5A1 1392/4885CAMK2A 379/4885PGR 1916/4885
US-12595267-B2 Preparation method for amide compound and application thereof in field of medicine EZH2, BMI1, EHMT1 SRD5A1 1222/4885CAMK2A 1545/4885PGR 3104/4885
US-20250289819-A1 CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF AKT1, AKT2, AKT3 SRD5A1 3449/4885CAMK2A 198/4885PGR 1965/4885
US-12624003-B2 Carboxylic acid containing indanyl compounds for the treatment of neurodegenerative diseases S1PR5, LPAR5, S1PR2 SRD5A1 219/4885CAMK2A 2214/4885PGR 1815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.