SCHEMBL2275281

SCHEMBL2275281

C=CCCCCCCCCC(O)=S

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.60
ABCC4 O15439 1/20 0.60
ALDH1A1 P00352 4/20 0.47
LMNA P02545 4/20 0.47
TSHR P16473 2/20 0.44
LPAR3 Q9UBY5 2/20 0.42
TRPA1 O75762 3/20 0.40
LPAR2 Q9HBW0 1/20 0.38
USP2 O75604 3/20 0.33
CYP3A4 P08684 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
RECQL P46063 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HPGD P15428 1/20 0.31
GMNN O75496 1/20 0.30
CYP1A2 P05177 1/20 0.30
POLB P06746 1/20 0.30
CYP2C9 P11712 1/20 0.30
ALOX15 P16050 1/20 0.30
APEX1 P27695 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10503959 1.00 MAPT (0.60) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL1481383 0.97
SCHEMBL1480898 0.90
SCHEMBL21195141 0.89 TSHR (0.64) MAPTABCC4ALDH1A1LMNATSHR
Hydrochloric Acid SCHEMBL10454227 0.87
Ammonia Solution, Strong SCHEMBL28432775 0.79 TSHR (0.42) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL18585414 0.79 MAPT (0.58) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL8609151 0.79 MAPT (0.58) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL8585201 0.79 MAPT (0.58) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL9007405 0.79 MAPT (0.58) MAPTABCC4ALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118806759-A Systemic formulations of pyridone derivatives for TG2 related diseases 福尔克博士药物有限责任公司 2024-10-22 CN disclosed
CN-115715187-B Systemic formulations of pyridone derivatives for TG2 related diseases 福尔克博士药物有限责任公司 2024-07-19 CN disclosed
CN-113262175-B Skin care compositions and methods of use thereof 尤尼根公司 2024-04-16 CN disclosed
CN-117580587-A Coronavirus nucleic acid vaccine based on sequences derived from SARS-CoV-2 Omikovia strain 苏州艾博生物科技有限公司 2024-02-20 CN disclosed
CN-117460827-A Nucleic acid vaccine for rabies 苏州艾博生物科技有限公司 2024-01-26 CN disclosed
CN-117202895-A Lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2023-12-08 CN disclosed
CN-117069785-A Lipid compounds and lipid nanoparticle compositions 中生复诺健生物科技(上海)有限公司 2023-11-17 CN disclosed
CN-117083291-A Coronavirus nucleic acid vaccine based on sequences derived from SARS-CoV-2Delta strain 苏州艾博生物科技有限公司 2023-11-17 CN disclosed
CN-117043343-A Nucleic acid vaccine for mutant coronaviruses 苏州艾博生物科技有限公司 2023-11-10 CN disclosed
CN-117003658-A Lipid Nanoparticle Compositions 苏州艾博生物科技有限公司 2023-11-07 CN disclosed
US-8669283-B2 Beta-lactones as antibacterial agents LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) 2014-03-11 US disclosed
US-8563598-B2 2013-10-22 US disclosed
US-20110196027-A1 BETA-LACTONES AS ANTIBACTERIAL AGENTS LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN 2011-08-11 US disclosed
EP-2254574-A1 BETA-LACTONES AS ANTIBACTERIAL AGENTS Ludwig-Maximilians-Universität München (DE) 2010-12-01 EP disclosed
WO-2009106211-A1 BETA-LACTONES AS ANTIBACTERIAL AGENTS LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) 2009-09-03 WO disclosed
US-4806675-A CATALYTIC ESTERIFICATION WITH HYDROXYALKANOIC AND THIOALKANOIC ACIDS; HEAT AND OXIDATION RESISTANCE MALLINCKRODT, INC. (US) 1989-02-21 US disclosed
US-4794138-A STABILIZERS OF ORGANIC MATERIAL NORMALLY SUSCEPTIBLE TO OXIDATIVE AND/OR THERMAL DETERIORATION MALLINCKRODT, INC. (US) 1988-12-27 US disclosed
US-4772741-A STABILIZERS FOR POLYMERS MILLINCKRODT, INC. (US) 1988-09-20 US disclosed
US-4734519-A STABILIZERS MALLINCKRODT, INC. (US) 1988-03-29 US disclosed
EP-0250087-A1 Pentaerythritol co-esters MALLINCKRODT, INC. (US) 1987-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110196027-A1 BETA-LACTONES AS ANTIBACTERIAL AGENTS ALG8, PGLS, GLA MAPT 3579/4885ABCC4 1552/4885ALDH1A1 4077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.