SCHEMBL2275427

SCHEMBL2275427

CC(C)COC(=O)C(C)C(=O)OCC(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.52
ALDH1A1 P00352 4/20 0.46
SMN1; SMN2 Q16637 2/20 0.38
TDP1 Q9NUW8 3/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
RAB9A P51151 1/20 0.36
P2RX4 Q99571 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
NFKB1 P19838 1/20 0.35
PTGS1 P23219 1/20 0.35
APEX1 P27695 1/20 0.35
THPO P40225 1/20 0.35
PMP22 Q01453 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15515336 0.90 TSHR (0.45) TSHRALDH1A1SMN1; SMN2KDM4EMAPT
SCHEMBL9478200 0.87 TSHR (0.52) TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL27709695 0.85 TSHR (0.50) TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL27101931 0.83 TSHR (0.59) TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL6515214 0.83 TSHR (0.43) TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL6515206 0.83 TSHR (0.43) TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL41548 0.82 TSHR (0.52) TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL30145011 0.82 TSHR (0.52) TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL7096884 0.81 TSHR (0.42) TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL11524614 0.80 TSHR (0.50) TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805647-A Catalyst composition for olefin polymerization and application thereof 北京肯佰恩科技发展有限公司 2022-07-29 CN claimed
EP-3053935-B1 CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION AND APPLICATION OF SAME CHINA PETROLEUM & CHEM CORP (CN) 2019-05-08 EP claimed
US-9822196-B2 Catalyst composition for olefin polymerization and application of same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-11-21 US claimed
CN-104513330-B A kind of catalyst systems for olefin polymerization and its application 中国石油化工股份有限公司 2017-07-28 CN claimed
CN-104513332-B Catalyst system and its application for olefinic polymerization 中国石油化工股份有限公司 2017-06-06 CN claimed
CN-104513327-B Olefin polymerization catalyst composition and applications thereof 中国石油化工股份有限公司 2017-02-15 CN claimed
US-20160244538-A1 CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION AND APPLICATION OF SAME BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2016-08-25 US claimed
EP-3053935-A1 CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION AND APPLICATION OF SAME China Petroleum & Chemical Corporation (CN) 2016-08-10 EP claimed
CN-105315390-A Catalyst composition for olefin polymerization and application thereof BEIJING COMBINE TECH CO LTD 2016-02-10 CN claimed
CN-104513330-A Catalyst system used in olefin polymerization and application thereof CHINA PETROLEUM & CHEMICAL 2015-04-15 CN claimed
CN-104513327-A Olefin polymerization catalyst composition and applications thereof CHINA PETROLEUM & CHEMICAL 2015-04-15 CN claimed
CN-104513332-A Catalyst system used in olefin polymerization and application thereof CHINA PETROLEUM & CHEMICAL 2015-04-15 CN claimed
CN-118909170-A Catalyst system for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2024-11-08 CN disclosed
CN-114805647-B Catalyst composition for olefin polymerization and application thereof 北京肯佰恩科技发展有限公司 2024-03-29 CN disclosed
CN-113912755-B Catalyst composition for olefin polymerization and application thereof 张一锴 2023-06-02 CN disclosed
CN-114805647-A Catalyst composition for olefin polymerization and application thereof 北京肯佰恩科技发展有限公司 2022-07-29 CN disclosed
EP-0360497-A2 Olefin polymerization catalyst, component thereof and process for polymerizing olefins with the catalyst, the film and injection-molded article from the obtained polyolefin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-03-28 EP disclosed
EP-0360491-A2 Olefin polymerization catalyst component, process for production thereof, olefin polymerization, catalyst, and process for polymerizing olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-03-28 EP disclosed
EP-0358516-A2 Process for producing cycloolefin random copolymers MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-03-14 EP disclosed
EP-0310394-A1 Process for producing cycloolefin random copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-04-05 EP disclosed