Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 4/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 4/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729454 | 0.91 | MAPK14 (0.39) | CNR1CNR2KDM4ETTK | |
| SCHEMBL22729453 | 0.91 | MAPK14 (0.39) | CNR1CNR2KDM4ETTK | |
| SCHEMBL22729415 | 0.84 | CNR2 (0.37) | CD38CNR1CNR2KDM4ETYK2 | |
| SCHEMBL22729416 | 0.84 | CNR2 (0.37) | CD38CNR1CNR2KDM4ETYK2 | |
| SCHEMBL19555168 | 0.69 | TYK2 (0.44) | CNR1CNR2TYK2 | |
| SCHEMBL19555169 | 0.69 | TYK2 (0.44) | CNR1CNR2TYK2 | |
| SCHEMBL23996089 | 0.68 | TYK2 (0.42) | CNR1CNR2TYK2 | |
| SCHEMBL22754972 | 0.68 | MAPT (0.47) | KDM4E | |
| SCHEMBL19554993 | 0.67 | TYK2 (0.42) | CNR1CNR2TYK2 | |
| SCHEMBL19554989 | 0.67 | TYK2 (0.42) | CNR1CNR2TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |