Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29839342 | 0.89 | KMT2A (0.53) | MAPTALDH1A1DGAT1CYP1A2CYP3A4 | |
| SCHEMBL22729798 | 0.89 | KMT2A (0.53) | MAPTALDH1A1DGAT1CYP1A2CYP3A4 | |
| SCHEMBL22729611 | 0.84 | UGCG (0.49) | MAPTALDH1A1DGAT1CYP1A2CYP3A4 | |
| SCHEMBL29839394 | 0.84 | UGCG (0.49) | MAPTALDH1A1DGAT1CYP1A2CYP3A4 | |
| SCHEMBL22729636 | 0.83 | MAPT (0.55) | MAPTALDH1A1DGAT1CYP1A2CYP3A4 | |
| SCHEMBL29839336 | 0.81 | PDE10A (0.49) | MAPTALDH1A1SMN1; SMN2RAB9APKM | |
| SCHEMBL22729625 | 0.81 | PDE10A (0.49) | MAPTALDH1A1SMN1; SMN2RAB9APKM | |
| SCHEMBL29839311 | 0.78 | UGCG (0.51) | MAPTALDH1A1SMN1; SMN2RAB9APKM | |
| SCHEMBL22729573 | 0.78 | UGCG (0.51) | MAPTALDH1A1SMN1; SMN2RAB9APKM | |
| SCHEMBL22729751 | 0.78 | MAPT (0.51) | MAPTALDH1A1DGAT1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |