Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 3/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 3/20 | 0.41 |
| ▸ | BRAF | P15056 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729573 | 1.00 | UGCG (0.51) | UGCGPDE10AAXLALDH1A1MAPT | |
| SCHEMBL29839394 | 0.93 | UGCG (0.49) | UGCGPDE10AAXLALDH1A1MAPT | |
| SCHEMBL22729611 | 0.93 | UGCG (0.49) | UGCGPDE10AAXLALDH1A1MAPT | |
| SCHEMBL22729625 | 0.90 | PDE10A (0.49) | PDE10AAXLALDH1A1MAPTLMNA | |
| SCHEMBL29839336 | 0.90 | PDE10A (0.49) | PDE10AAXLALDH1A1MAPTLMNA | |
| SCHEMBL22729798 | 0.82 | KMT2A (0.53) | PDE10AALDH1A1MAPTLMNAPKM | |
| SCHEMBL29839342 | 0.82 | KMT2A (0.53) | PDE10AALDH1A1MAPTLMNAPKM | |
| SCHEMBL22729551 | 0.79 | MAPT (0.51) | PDE10AALDH1A1MAPTLMNAMITF | |
| SCHEMBL22755057 | 0.78 | MAPT (0.53) | ALDH1A1MAPTLMNAMITFPOLB | |
| SCHEMBL22729397 | 0.78 | UGCG (0.67) | UGCGALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459325-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11459325-B2 | Heterocyclic compound | GBA1, GBA2, GALC | UGCG 8/4885PDE10A 636/4885AXL 4608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.