Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 9/20 | 0.37 |
| ▸ | MGLL | Q99685 | 5/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22754980 | 0.82 | MGLL (0.39) | MGLLHCRTR1HCRTR2HSD11B1 | |
| SCHEMBL22754886 | 0.82 | MGLL (0.37) | MGLL | |
| SCHEMBL22755305 | 0.81 | MGLL (0.42) | MGLL | |
| SCHEMBL22755029 | 0.81 | MGLL (0.42) | MGLL | |
| SCHEMBL22755296 | 0.80 | MGLL (0.40) | MGLLHSD11B1 | |
| SCHEMBL22755028 | 0.80 | MGLL (0.36) | MGLLHCRTR1HCRTR2HSD11B1 | |
| SCHEMBL22754925 | 0.80 | MGLL (0.41) | MGLLHSD11B1 | |
| SCHEMBL22729525 | 0.79 | MGLL (0.36) | PDE2AMGLLSLC6A9HCRTR1HCRTR2 | |
| SCHEMBL22754906 | 0.79 | MGLL (0.39) | MGLL | |
| SCHEMBL22755286 | 0.78 | MGLL (0.36) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |